Vistaril and Vitamin d3 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vistaril (hydroxyzine hydrochloride) and Vitamin d3 (cholecalciferol). Common drug interactions include blood calcium increased among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Vistaril and Vitamin d3. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Vistaril?

Vistaril has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 9,565 Vistaril users. Check the latest studies of Vistaril.

What is Vitamin d3?

Vitamin d3 has active ingredients of cholecalciferol. It is often used in heart health. eHealthMe is studying from 32,172 Vitamin d3 users. Check the latest studies of Vitamin d3.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

52 people who take Vistaril and Vitamin d3 together, and have interactions are studied.

Vistaril and Vitamin d3 drug interactions.

What are the common drug interactions of Vistaril and Vitamin D3, by gender? *:

female:

Blood calcium increased
Blood creatinine increased
Blood glucose increased
Blood immunoglobulin g increased
Carbon dioxide decreased
Dehydration (dryness resulting from the removal of water)
Eosinophil count decreased
Eosinophilia (eosinophil count in the peripheral blood exceeds)
Hyperkalaemia (damage to or disease of the kidney)
Hypernatraemia (an abnormally high plasma concentration of sodium ions)

male:

Fatigue (feeling of tiredness)
Hypoaesthesia (reduced sense of touch or sensation)
Malaise (a feeling of general discomfort or uneasiness)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Tremor (trembling or shaking movements in one or more parts of your body)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Muscle spasms (muscle contraction)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Vomiting
Abdominal pain

What are the common drug interactions of Vistaril and Vitamin D3, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Injection site pain
Somnolence (a state of near-sleep, a strong desire for sleep)

20-29:

Decreased interest
Depression
Device dislocation
Fatigue (feeling of tiredness)
Somnolence (a state of near-sleep, a strong desire for sleep)
Medical device complication

30-39:

Anion gap increased
Basophil count decreased
Blood alkaline phosphatase increased
Blood calcium increased
Blood creatinine increased
Blood glucose increased
Blood immunoglobulin g increased
Carbon dioxide decreased
Dehydration (dryness resulting from the removal of water)
Eosinophil count decreased

40-49:

Arthralgia (joint pain)
Injection site erythema (redness at injection site)
Injection site pruritus (severe itching at injection site)
Injection site swelling
Back pain
Abdominal pain
Asthenia (weakness)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chest discomfort
Chest pain

50-59:

Blood chloride decreased
Blood cholesterol increased
Blood glucose increased
Blood pressure decreased
Blood sodium decreased
Body temperature increased
Borderline personality disorder
Bronchial wall thickening
Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Chills (felling of cold)

60+:

Fall
Fatigue (feeling of tiredness)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Ascites (accumulation of fluid in the abdominal cavity)
Back injury
Bacteraemia (presence of bacteria in the blood)
Blood cholesterol increased
Body temperature decreased
Chronic kidney disease
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)

What are the existing conditions these people have? *

Pain: 8 people, 15.38%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 7 people, 13.46%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 13.46%
Nausea (feeling of having an urge to vomit): 6 people, 11.54%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 7.69%
Psoriasis (immune-mediated disease that affects the skin): 4 people, 7.69%
Depression: 4 people, 7.69%
Wheezing (a high-pitched whistling sound made while you breath): 3 people, 5.77%
Sleep Disorder: 3 people, 5.77%
Multiple Myeloma (cancer of the plasma cells): 3 people, 5.77%

* Approximation only. Some reports may have incomplete information.

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