Vistide and Methotrexate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vistide (cidofovir) and Methotrexate (methotrexate sodium). Common drug interactions include disease recurrence among females and stomatitis among males.

The phase IV clinical study analyzes what interactions people have when they take Vistide and Methotrexate. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Vistide?

Vistide has active ingredients of cidofovir. eHealthMe is studying from 624 Vistide users. Check the latest studies of Vistide.

What is Methotrexate?

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. eHealthMe is studying from 604,312 Methotrexate users. Check the latest studies of Methotrexate.



On Jul, 13, 2026

18 people who take Vistide and Methotrexate together, and have interactions are studied.

Vistide and Methotrexate drug interactions.

What are the common drug interactions of Vistide and Methotrexate, by gender? *:

female:

  1. Disease recurrence
  2. Multi-organ failure (multisystem organ failure)
  3. Adenovirus infection
  4. Candidal infection (fungal infection)
  5. Cytomegalovirus infection
  6. Diarrhoea
  7. Enteritis (inflammation of the small intestine)
  8. Febrile infection (infection with temperature rise)
  9. Gastroenteritis (inflammation of stomach and intestine)
  10. Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)

male:

  1. Stomatitis (inflammation of mucous membrane of mouth)
  2. Adenovirus infection
  3. B-cell lymphoma (blood cancer affecting b cells)
  4. Disease progression
  5. Epstein-barr virus infection
  6. Influenza
  7. Joint stiffness
  8. Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  9. Non-hodgkin's lymphoma (malignant (cancer) cells form in the lymph system)
  10. Oedema peripheral (superficial swelling)

What are the common drug interactions of Vistide and Methotrexate, by age (0-1 to 60+)? *:

0-1:

  1. Multi-organ failure (multisystem organ failure)
  2. Sepsis (a severe blood infection that can lead to organ failure and death)

2-9:

  1. Adenovirus infection
  2. Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
  3. Epistaxis (bleed from the nose)
  4. Lip haemorrhage (bleeding lip)
  5. Respiratory distress (difficulty in breathing)
  6. Stomatitis (inflammation of mucous membrane of mouth)
  7. Acute respiratory distress syndrome
  8. Disease progression
  9. Influenza
  10. Leukaemia relapse (failing of blood cancer or bone marrow cancer)

10-19:

n/a

20-29:

n/a

30-39:

  1. Renal impairment (severely reduced kidney function)

40-49:

n/a

50-59:

n/a

60+:

  1. Therapeutic response decreased (less preventive response)
  2. Uveitis (inflammation of the uvea)
  3. B-cell lymphoma (blood cancer affecting b cells)
  4. Epstein-barr virus infection
  5. Joint stiffness
  6. Non-hodgkin's lymphoma (malignant (cancer) cells form in the lymph system)
  7. Oedema peripheral (superficial swelling)
  8. Osteopenia (a condition where bone mineral density is lower than normal)
  9. Stomatitis (inflammation of mucous membrane of mouth)

What are the existing conditions these people have? *

  1. Lymphoma (cancer that begins in immune system cells): 2 people, 11.11%
  2. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 1 person, 5.56%
  3. Cystitis Haemorrhagic (blood in the urine and painful voiding): 1 person, 5.56%
  4. Bk Virus Infection: 1 person, 5.56%
  5. Adenovirus Infection: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Vistide and Methotrexate?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vistide and Methotrexate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vistide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Methotrexate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vistide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Methotrexate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on cidofovir and methotrexate sodium (the active ingredients of Vistide and Methotrexate, respectively), and Vistide and Methotrexate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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