Vitamin b1 and Premarin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vitamin b1 (thiamine) and Premarin (estrogens, conjugated). Common drug interactions include facial bones fracture among females and abscess rupture among males.

The phase IV clinical study analyzes what interactions people have when they take Vitamin b1 and Premarin. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Vitamin b1?

Vitamin b1 has active ingredients of thiamine. It is often used in fatigue. eHealthMe is studying from 4,661 Vitamin b1 users. Check the latest studies of Vitamin b1.

What is Premarin?

Premarin has active ingredients of estrogens, conjugated. It is often used in hormone replacement therapy. eHealthMe is studying from 99,630 Premarin users. Check the latest studies of Premarin.

On Jul, 18, 2026

27 people who take Vitamin b1 and Premarin together, and have interactions are studied.

Vitamin b1 and Premarin drug interactions.

What are the common drug interactions of Vitamin B1 and Premarin, by gender? *:

female:

Facial bones fracture (bone fracture of face)
Lower limb fracture
Osteoporosis (bones weak and more likely to break)
Pain in extremity
Type 2 diabetes mellitus
Upper limb fracture
Pneumonia
Back pain
Limb discomfort (discomfort in leg)
Mobility decreased (ability to move is reduced)

male:

Abscess rupture (pus release from the point of abscess)
Acquired porphyria (group of disorders that result in a build up of chemicals called porphyrins in the body)
Blood glucose increased
Bone disorder
Bone fragmentation
Bone marrow granuloma (collection of inflammatory cells in bone marrow)
Breast cancer recurrent
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Central nervous system lymphoma (cancer of central nervous system forms in lymph tissue)
Cholangitis chronic (long lasting infection of the bile duct)

What are the common drug interactions of Vitamin B1 and Premarin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Arthralgia (joint pain)
Asthenia (weakness)
Confusional state
Diarrhoea
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dizziness
Pain in extremity
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Weight decreased

40-49:

Application site discharge
Application site erythema (redness of the skin at application site)
Application site scab (hard coating on the skin formed at application site)
Application site scar
Application site swelling
Application site ulcer
Application site vesicles (small bubble within a cell at application site)
Burning sensation
Fall
Gait disturbance

50-59:

Pallor
Pancreatic insufficiency
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pathological fracture (broken bone caused by disease)
Periodontal disease (disease that attacks the gum and bone and around the teeth)
Pneumatosis intestinalis (air or gas in an intestine)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)
Renal cyst (kidney cyst)
Restless legs syndrome (a powerful urge to move your legs)

60+:

Back pain
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Pain
Peripheral swelling
Pneumonia
Spinal pain (pain in spine)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Balance disorder
Cardiac failure congestive
Cystitis (inflammation of the wall of the bladder)

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 10 people, 37.04%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 22.22%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 11.11%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 11.11%
Pain: 3 people, 11.11%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 11.11%
Limb Discomfort (discomfort in leg): 2 people, 7.41%
Back Pain: 2 people, 7.41%
Cardiac Disorder: 2 people, 7.41%
Depression: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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