Vitamin b12 and Tepezza drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vitamin b12 (cobalamin) and Tepezza (teprotumumab-trbw). Common drug interactions include nausea among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Vitamin b12 and Tepezza. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Vitamin b12?

Vitamin b12 has active ingredients of cobalamin. It is often used in vitamin b12 deficiency. eHealthMe is studying from 121,681 Vitamin b12 users. Check the latest studies of Vitamin b12.

What is Tepezza?

Tepezza has active ingredients of teprotumumab-trbw. eHealthMe is studying from 3,632 Tepezza users. Check the latest studies of Tepezza.



On Jul, 26, 2026

35 people who take Vitamin b12 and Tepezza together, and have interactions are studied.

Vitamin b12 and Tepezza drug interactions.

What are the common drug interactions of Vitamin B12 and Tepezza, by gender? *:

female:

  1. Nausea (feeling of having an urge to vomit)
  2. Diarrhoea
  3. Muscle spasms (muscle contraction)
  4. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  5. Confusional state
  6. Deafness
  7. Erythema (redness of the skin)
  8. Headache (pain in head)
  9. Somnolence (a state of near-sleep, a strong desire for sleep)
  10. Vision blurred

male:

  1. Diarrhoea
  2. Abnormal behaviour
  3. Urinary tract infection
  4. Blood glucose increased
  5. Dyspepsia (indigestion)
  6. Headache (pain in head)
  7. Hypertension (high blood pressure)
  8. Nausea (feeling of having an urge to vomit)
  9. Agitation (state of anxiety or nervous excitement)
  10. Deafness

What are the common drug interactions of Vitamin B12 and Tepezza, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Headache (pain in head)
  2. Muscle spasms (muscle contraction)
  3. Nausea (feeling of having an urge to vomit)

40-49:

  1. Diarrhoea
  2. Nausea (feeling of having an urge to vomit)
  3. Blood glucose increased
  4. Dyspepsia (indigestion)
  5. Headache (pain in head)
  6. Hypertension (high blood pressure)
  7. Abdominal pain upper
  8. Erythema (redness of the skin)
  9. Migraine (headache)
  10. Muscle tightness

50-59:

  1. Abnormal behaviour
  2. Diarrhoea
  3. Agitation (state of anxiety or nervous excitement)
  4. Onychoclasis (breaking of the nails)
  5. Schizophrenia (a mental disorder characterized by a breakdown of thought processes)
  6. Urinary tract infection

60+:

  1. Deafness
  2. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  3. Constipation
  4. Decreased appetite
  5. Diplopia (double vision)
  6. Dizziness
  7. Dry skin
  8. Dysphonia (speech disorder attributable to a disorder of phonation)
  9. Dyspnoea (difficult or laboured respiration)
  10. Ear pain

What are the existing conditions these people have? *

  1. Endocrine Ophthalmopathy (increased water content of retroocular orbital tissues; associated with thyroid disease, usually hyperthyroidism): 31 people, 88.57%
  2. High Blood Pressure: 2 people, 5.71%
  3. Basedow's Disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones): 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

Do you take Vitamin b12 and Tepezza?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vitamin b12 and Tepezza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vitamin b12:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tepezza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vitamin b12 and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tepezza and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on cobalamin and teprotumumab-trbw (the active ingredients of Vitamin b12 and Tepezza, respectively), and Vitamin b12 and Tepezza (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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