Vitamin b12 and Toprol-xl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vitamin b12 (cobalamin) and Toprol-xl (metoprolol succinate). Common drug interactions include bursitis among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Vitamin b12 and Toprol-xl. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Vitamin b12?

Vitamin b12 has active ingredients of cobalamin. It is often used in vitamin b12 deficiency. eHealthMe is studying from 121,681 Vitamin b12 users. Check the latest studies of Vitamin b12.

What is Toprol-xl?

Toprol-xl has active ingredients of metoprolol succinate. It is often used in high blood pressure. eHealthMe is studying from 40,636 Toprol-xl users. Check the latest studies of Toprol-xl.

On Jul, 19, 2026

39 people who take Vitamin b12 and Toprol-xl together, and have interactions are studied.

Vitamin b12 and Toprol-xl drug interactions.

What are the common drug interactions of Vitamin B12 and Toprol-Xl, by gender? *:

female:

Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Cardiac failure congestive
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Drug ineffective
Epistaxis (bleed from the nose)
Fibromyalgia (a long-term condition which causes pain all over the body)
Haematochezia (passage of stools containing blood)
Heart rate increased
Macular degeneration (painless eye condition that leads to the gradual loss of central vision)

male:

Pain
Arthralgia (joint pain)
Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Abdominal pain upper
Alopecia (absence of hair from areas of the body)
Amyloidosis (a tumour within which amyloid is produced)
Anal fissure
Androgens decreased
Aortic dilatation

What are the common drug interactions of Vitamin B12 and Toprol-Xl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal pain
Abdominal pain lower
Cardiac failure congestive
Cellulitis (infection under the skin)
Constipation
Drug dependence
Drug exposure during pregnancy
Drug ineffective
Emotional disorder
Gestational diabetes (diabetes in pregnancy)

50-59:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dental caries
Dental fistula
Dental plaque (film of mucus and bacteria deposited on the teeth that encourages the development of dental caries)
Depression
Device failure
Disease progression
Dysaesthesia (abnormal sensation)
Ejection fraction decreased (systolic heart failure)
Encopresis (inability to control the elimination of stool)

60+:

Nausea (feeling of having an urge to vomit)
Hypersensitivity
Rash generalised (rash on most of body parts)
Renal failure (kidney dysfunction)
Abdominal pain
Angioedema (rapid swelling of the dermis)
Blood alkaline phosphatase increased
Blood glucose increased
Burning sensation
Cardiac murmur (an heart sound in valve abnormality)

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 7.69%
Breast Cancer Metastatic: 3 people, 7.69%
Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 2 people, 5.13%
Lung Cancer - Non-Small Cell (lung cancer): 2 people, 5.13%
Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 2 people, 5.13%
Depression: 2 people, 5.13%
Bone Disorder: 2 people, 5.13%

* Approximation only. Some reports may have incomplete information.

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