Vitamin c and Duphalac drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vitamin c (l-ascorbic acid) and Duphalac (lactulose). Common drug interactions include pneumonitis among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Vitamin c and Duphalac. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Vitamin c?

Vitamin c has active ingredients of l-ascorbic acid. It is often used in immune response. eHealthMe is studying from 92,472 Vitamin c users. Check the latest studies of Vitamin c.

What is Duphalac?

Duphalac has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 5,152 Duphalac users. Check the latest studies of Duphalac.



On Jul, 08, 2026

21 people who take Vitamin c and Duphalac together, and have interactions are studied.

Vitamin c and Duphalac drug interactions.

What are the common drug interactions of Vitamin C and Duphalac, by gender? *:

female:

  1. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  2. Renal failure (kidney dysfunction)
  3. Ileus (a painful obstruction of the ileum or other part of the intestine)
  4. Pleural effusion (water on the lungs)
  5. Vomiting
  6. Lung infection
  7. Abdominal distension
  8. Abdominal pain
  9. Adenomyosis (presence of ectopic glandular tissue found in muscle)
  10. Ammonia increased

male:

  1. Anaemia (lack of blood)
  2. Hypercalcaemia (elevated calcium (ca+) level in the blood)
  3. Hypokalaemia (low potassium)
  4. Disseminated intravascular coagulation (systemic activation of blood coagulation)
  5. Lung infection
  6. Myelosuppression (a decrease in the production of blood cells)
  7. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  8. Pneumonia
  9. Thrombocytopenia (decrease of platelets in blood)

What are the common drug interactions of Vitamin C and Duphalac, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Ileus (a painful obstruction of the ileum or other part of the intestine)
  2. Anxiety
  3. Chronic kidney disease
  4. Depression
  5. Incontinence (lack of moderation or self-control)

50-59:

  1. Pleural effusion (water on the lungs)
  2. Vomiting
  3. Lung infection
  4. Pneumonia
  5. Abdominal distension
  6. Abdominal pain
  7. Adenomyosis (presence of ectopic glandular tissue found in muscle)
  8. Ammonia increased
  9. Anaemia (lack of blood)
  10. Anion gap increased

60+:

  1. Pneumonia
  2. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  3. Renal failure (kidney dysfunction)
  4. Anaemia (lack of blood)
  5. Hypercalcaemia (elevated calcium (ca+) level in the blood)
  6. Hypokalaemia (low potassium)
  7. Lung infection
  8. Myelosuppression (a decrease in the production of blood cells)
  9. Myositis (inflammation of the muscles)
  10. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)

What are the existing conditions these people have? *

  1. Lung Cancer - Non-Small Cell (lung cancer): 9 people, 42.86%
  2. Dyspnea (difficult or laboured breathing): 6 people, 28.57%
  3. Stress And Anxiety: 5 people, 23.81%
  4. Insomnia (sleeplessness): 5 people, 23.81%
  5. High Blood Cholesterol: 5 people, 23.81%
  6. High Blood Pressure: 4 people, 19.05%
  7. Pain: 4 people, 19.05%
  8. Atherosclerosis (disorder of the arteries): 2 people, 9.52%
  9. Chest Pain: 2 people, 9.52%
  10. Coughing Up Blood: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

Do you take Vitamin c and Duphalac?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vitamin c and Duphalac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vitamin c:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Duphalac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vitamin c and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Duphalac and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on l-ascorbic acid and lactulose (the active ingredients of Vitamin c and Duphalac, respectively), and Vitamin c and Duphalac (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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