Vitamin c and Epival drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vitamin c (l-ascorbic acid) and Epival (divalproex sodium). Common drug interactions include wrist fracture among females and convulsion among males.

The phase IV clinical study analyzes what interactions people have when they take Vitamin c and Epival. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Vitamin c?

Vitamin c has active ingredients of l-ascorbic acid. It is often used in immune response. eHealthMe is studying from 92,472 Vitamin c users. Check the latest studies of Vitamin c.

What is Epival?

Epival has active ingredients of divalproex sodium. It is often used in epilepsy. eHealthMe is studying from 1,088 Epival users. Check the latest studies of Epival.

On Jul, 26, 2026

22 people who take Vitamin c and Epival together, and have interactions are studied.

What are the common drug interactions of Vitamin C and Epival, by gender? *:

female:

Wrist fracture
Ligament sprain (ligament stretched)
Abscess (pus)
Alopecia (absence of hair from areas of the body)
Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Blood pressure increased
Blood thyroid stimulating hormone decreased
Breast abscess
Drug hypersensitivity
Hepatic enzyme increased

male:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Influenza
Memory impairment
Postictal state
Pyrexia (fever)

What are the common drug interactions of Vitamin C and Epival, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abscess (pus)
Alopecia (absence of hair from areas of the body)
Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Blood pressure increased
Blood thyroid stimulating hormone decreased
Breast abscess
Drug hypersensitivity
Fall
Hepatic enzyme increased
Hidradenitis (chronic disease of a type of sweat gland)

40-49:

Abscess (pus)
Alopecia (absence of hair from areas of the body)
Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Blood pressure increased
Blood thyroid stimulating hormone decreased
Breast abscess
Drug hypersensitivity
Fall
Hepatic enzyme increased
Infusion related reaction

50-59:

n/a

60+:

Ankle fracture
Dyspnoea (difficult or laboured respiration)
Fall
Ligament sprain (ligament stretched)
Pain

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 13 people, 59.09%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 4 people, 18.18%
Weight Decreased: 2 people, 9.09%
Osteoporosis (bones weak and more likely to break): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Vitamin c and Epival?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously