Vitamin d3 and Pentoxifylline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vitamin d3 (cholecalciferol) and Pentoxifylline (pentoxifylline). Common drug interactions include alopecia among females and fall among males.

The phase IV clinical study analyzes what interactions people have when they take Vitamin d3 and Pentoxifylline. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Vitamin d3?

Vitamin d3 has active ingredients of cholecalciferol. It is often used in heart health. eHealthMe is studying from 32,172 Vitamin d3 users. Check the latest studies of Vitamin d3.

What is Pentoxifylline?

Pentoxifylline has active ingredients of pentoxifylline. eHealthMe is studying from 5,997 Pentoxifylline users. Check the latest studies of Pentoxifylline.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

23 people who take Vitamin d3 and Pentoxifylline together, and have interactions are studied.

Vitamin d3 and Pentoxifylline drug interactions.

What are the common drug interactions of Vitamin D3 and Pentoxifylline, by gender? *:

female:

Alopecia (absence of hair from areas of the body)
Anaemia (lack of blood)
Diarrhoea
Fatigue (feeling of tiredness)
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Peripheral swelling
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Sinusitis (inflammation of sinus)
Acute respiratory failure

male:

Fall
Femur fracture
Dacryostenosis acquired (obstruction of the nasolacrimal duct-acquired)
Diarrhoea
Ear infection
Erectile dysfunction
Hepatic enzyme increased
Hepatic lesion
Jaundice neonatal (yellowing of skin in neonate)
Lip disorder (disease of lip)

What are the common drug interactions of Vitamin D3 and Pentoxifylline, by age (0-1 to 60+)? *:

0-1:

Abnormal faeces (abnormal stool)
Dacryocanaliculitis (1. inflammation of the lacrimal ducts. 2. inflammation of the lacrimal sac and lacrimal canaliculi)
Dacryostenosis acquired (obstruction of the nasolacrimal duct-acquired)
Ear infection
Jaundice neonatal (yellowing of skin in neonate)
Lip disorder (disease of lip)
Nasopharyngitis (inflammation of the nasopharynx)
Neonatal aspiration (aspiration by neonate)
Sinusitis (inflammation of sinus)
Tremor (trembling or shaking movements in one or more parts of your body)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Fall
Femur fracture
Hip fracture
Spinal fracture (fracture in one of vertebrae)
Beta haemolytic streptococcal infection (infection with streptococcus pyogenes, a beta-haemolytic bacterium cause mild to moderately severe respiratory tract, skin, and soft tissue)
Haemorrhage in pregnancy (bleeding in pregnancy)
Herpes virus infection
Induced labour (prematurely stimulating childbirth in a woman)
Postpartum haemorrhage (bleeding in woman after she has given birth)
Pre-eclampsia (high blood pressure and significant amounts of protein in the urine of a pregnant woman)

50-59:

Somnolence (a state of near-sleep, a strong desire for sleep)
Cerebral haemorrhage (bleeding within the brain)
Erectile dysfunction
Haemoglobin decreased
Migraine (headache)
Night sweats (sweating in night)
Penis disorder
Platelet count decreased
White blood cell count decreased

60+:

Alopecia (absence of hair from areas of the body)
Anaemia (lack of blood)
Bladder dilatation
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Bradycardia (abnormally slow heart action)
Cardiac arrest
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chest pain
Chorea (abnormal involuntary movement disorder)
Constipation

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 17.39%
High Blood Pressure: 3 people, 13.04%
High Blood Cholesterol: 3 people, 13.04%
Bladder Disorder: 3 people, 13.04%
Primary Myelofibrosis (primary disorder of the bone marrow): 2 people, 8.70%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 2 people, 8.70%
Pain: 2 people, 8.70%
Mood Swings (an extreme or rapid change in mood): 2 people, 8.70%
Memory Loss: 2 people, 8.70%
Heart Disease: 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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