Vitamin e and Aredia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vitamin e (tocopherols and tocotrienols) and Aredia (pamidronate disodium). Common drug interactions include bone disorder among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Vitamin e and Aredia. It is created by eHealthMe based on reports of 94 people who take the same drugs from the FDA, and is updated regularly.

What is Vitamin e?

Vitamin e has active ingredients of tocopherols and tocotrienols. It is often used in vitamin supplementation. eHealthMe is studying from 42,279 Vitamin e users. Check the latest studies of Vitamin e.

What is Aredia?

Aredia has active ingredients of pamidronate disodium. It is often used in breast cancer. eHealthMe is studying from 15,364 Aredia users. Check the latest studies of Aredia.

On Jul, 05, 2026

94 people who take Vitamin e and Aredia together, and have interactions are studied.

What are the common drug interactions of Vitamin E and Aredia, by gender? *:

female:

Bone disorder
Injury
Osteonecrosis of jaw (death of bone of jaw)
Pleural effusion (water on the lungs)
Dyspnoea (difficult or laboured respiration)
Impaired healing
Back pain
Osteomyelitis (infection of bone)
Chest pain
Pain in jaw

male:

Pain
Anxiety
Osteomyelitis (infection of bone)
Sinusitis (inflammation of sinus)
Injury
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Syncope (loss of consciousness with an inability to maintain postural tone)
Chest pain
Exposed bone in jaw
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

What are the common drug interactions of Vitamin E and Aredia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Anxiety
Bone disorder
Osteonecrosis of jaw (death of bone of jaw)
Pain
Syncope (loss of consciousness with an inability to maintain postural tone)
Actinic keratosis (skin disease due to sun exposure)
Balance disorder
Compression fracture (fracture due to pressure caused by injury)
Decreased interest
Dental caries

20-29:

Anaemia (lack of blood)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dyspnoea (difficult or laboured respiration)
Exostosis (formation of new bone on the surface of a bone)
Metastases to spine (cancer spreads to spine)
Neuropathy peripheral (surface nerve damage)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteonecrosis of jaw (death of bone of jaw)
Pain
Vertebral foraminal stenosis (narrowing of the intervertebral foramen)

30-39:

Abdominal pain
Acute sinusitis
Anaemia (lack of blood)
Aneurysm (enlargement of an artery caused by a weakening of the artery wall)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Anxiety
Aortic calcification (aortic calcification sign of heart valve disease)
Aortic valve sclerosis (narrowing of the aortic valve)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Arthralgia (joint pain)

40-49:

Pain
Dyspnoea (difficult or laboured respiration)
Dysarthria (speech disorder)
Hypertension (high blood pressure)
Anaemia (lack of blood)
Anxiety
Chest pain
Hyperlipidaemia (presence of excess lipids in the blood)
Mucosal inflammation (infection of mucous membrane)
Neuropathy peripheral (surface nerve damage)

50-59:

Bone disorder
Cardiac failure congestive
Osteonecrosis of jaw (death of bone of jaw)
Osteosclerosis (an elevation in bone density)
Spinal osteoarthritis (joint cartilage loss in spine)
Back pain
Cardiomyopathy (weakening of the heart muscle)
Exposed bone in jaw
Pleural effusion (water on the lungs)
Cellulitis (infection under the skin)

60+:

Bone disorder
Anxiety
Neutropenia (an abnormally low number of neutrophils)
Back pain
Haemoglobin decreased
Infection
Osteonecrosis (death of bone)
Fall
Injury
Pain in jaw

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 37 people, 39.36%
Metastases To Bone (cancer spreads to bone): 19 people, 20.21%
Breast Cancer Metastatic: 17 people, 18.09%
Osteoporosis (bones weak and more likely to break): 13 people, 13.83%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 11 people, 11.70%
Pain: 10 people, 10.64%
Stress And Anxiety: 9 people, 9.57%
High Blood Cholesterol: 9 people, 9.57%
High Blood Pressure: 8 people, 8.51%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 6 people, 6.38%

* Approximation only. Some reports may have incomplete information.

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