Vitamin e and Capoten drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vitamin e (tocopherols and tocotrienols) and Capoten (captopril). Common drug interactions include dyspepsia among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Vitamin e and Capoten. It is created by eHealthMe based on reports of 56 people who take the same drugs from the FDA, and is updated regularly.

What is Vitamin e?

Vitamin e has active ingredients of tocopherols and tocotrienols. It is often used in vitamin supplementation. eHealthMe is studying from 42,279 Vitamin e users. Check the latest studies of Vitamin e.

What is Capoten?

Capoten has active ingredients of captopril. It is often used in high blood pressure. eHealthMe is studying from 2,954 Capoten users. Check the latest studies of Capoten.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

56 people who take Vitamin e and Capoten together, and have interactions are studied.

Vitamin e and Capoten drug interactions.

What are the common drug interactions of Vitamin E and Capoten, by gender? *:

female:

Dyspepsia (indigestion)
Dyspnoea (difficult or laboured respiration)
Electrocardiogram t wave inversion
Extrasystoles
Fatigue (feeling of tiredness)
Flatulence (flatus expelled through the anus)
Fluid retention (an abnormal accumulation of fluid in the blood)
Flushing (the warm, red condition of human skin)
Gangrene (body tissue dies)
Gastro-oesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

male:

Cardiac failure congestive
Fall
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Cataract (clouding of the lens inside the eye)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Headache (pain in head)
Memory impairment
Muscle spasms (muscle contraction)

What are the common drug interactions of Vitamin E and Capoten, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Lower respiratory tract infection

20-29:

n/a

30-39:

n/a

40-49:

Asthenia (weakness)
Balance disorder
Bone pain
Breast cancer
Breast mass
Hot flush (sudden feelings of heat)
Fibrocystic breast disease (a condition causing breast pain, cysts, and noncancerous breast lumps, affects many women)
Endometrial hypertrophy (enlargement of uterine wall from the increase in size of its cells)
Vaginal haemorrhage (vaginal bleeding)

50-59:

Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Immunodeficiency
Nausea (feeling of having an urge to vomit)
Ovarian cancer (cancer of ovary)
Parosmia (distortion of the sense of smell, as in smelling odours that are not present)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Renal tubular necrosis (death of kidney tubules)
Shock hypoglycaemic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to less sugar in body)

60+:

Cardiac failure congestive
Dysarthria (speech disorder)
Nausea (feeling of having an urge to vomit)
Abdominal pain upper
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Asthma
Cataract (clouding of the lens inside the eye)
Chest pain
Chest pressure sensation (feeling of pressure on chest)
Collapse (sudden functional breakdown)

What are the existing conditions these people have? *

Osteopenia (a condition where bone mineral density is lower than normal): 5 people, 8.93%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 5 people, 8.93%
Migraine (headache): 5 people, 8.93%
Menopausal Symptoms: 5 people, 8.93%
Depression: 5 people, 8.93%
Type 2 Diabetes: 3 people, 5.36%

* Approximation only. Some reports may have incomplete information.

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