Vitamin e and Exforge drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vitamin e (tocopherols and tocotrienols) and Exforge (amlodipine besylate; valsartan). Common drug interactions include chronic kidney disease among females and balance disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Vitamin e and Exforge. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Vitamin e?

Vitamin e has active ingredients of tocopherols and tocotrienols. It is often used in vitamin supplementation. eHealthMe is studying from 42,279 Vitamin e users. Check the latest studies of Vitamin e.

What is Exforge?

Exforge has active ingredients of amlodipine besylate; valsartan. It is often used in high blood pressure. eHealthMe is studying from 13,350 Exforge users. Check the latest studies of Exforge.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

39 people who take Vitamin e and Exforge together, and have interactions are studied.

Vitamin e and Exforge drug interactions.

What are the common drug interactions of Vitamin E and Exforge, by gender? *:

female:

Chronic kidney disease
Back pain
Renal failure (kidney dysfunction)
Mobility decreased (ability to move is reduced)
Rash
Anxiety
Asthma
Cellulitis (infection under the skin)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Depression

male:

Balance disorder
Chronic kidney disease
Dyspnoea (difficult or laboured respiration)
Face injury
Head injury
Headache (pain in head)
Renal injury (kidney injury)
Rhinorrhoea (watery mucus discharge from the nose)
Diarrhoea
Fall

What are the common drug interactions of Vitamin E and Exforge, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chronic kidney disease
Myalgia (muscle pain)
Nephropathy (damage to or disease of a kidney)
Nuclear magnetic resonance imaging brain
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

50-59:

Cough
Dyspnoea (difficult or laboured respiration)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Rhinorrhoea (watery mucus discharge from the nose)

60+:

Back pain
Chronic kidney disease
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Ligament sprain (ligament stretched)
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Oedema peripheral (superficial swelling)
Pneumonia
Restless legs syndrome (a powerful urge to move your legs)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 14 people, 35.90%
High Blood Pressure: 13 people, 33.33%
Pain: 13 people, 33.33%
High Blood Cholesterol: 9 people, 23.08%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 15.38%
Osteoporosis (bones weak and more likely to break): 6 people, 15.38%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 5 people, 12.82%
Diabetes: 5 people, 12.82%
Asthma: 5 people, 12.82%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 10.26%

* Approximation only. Some reports may have incomplete information.

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