Vitamin e and Exjade drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Vitamin e (tocopherols and tocotrienols) and Exjade (deferasirox). Common drug interactions include vomiting among females and abdominal discomfort among males.
The phase IV clinical study analyzes what interactions people have when they take Vitamin e and Exjade. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.
What is Vitamin e?
Vitamin e has active ingredients of tocopherols and tocotrienols. It is often used in vitamin supplementation. eHealthMe is studying from 42,279 Vitamin e users. Check the latest studies of Vitamin e.
What is Exjade?
Exjade has active ingredients of deferasirox. It is often used in iron overload. eHealthMe is studying from 29,456 Exjade users. Check the latest studies of Exjade.
34 people who take Vitamin e and Exjade together, and have interactions are studied.

What are the common drug interactions of Vitamin E and Exjade, by gender? *:
female:
- Vomiting
- Abdominal pain
- Rash
- Asthenia (weakness)
- Blood urine present
- Burning sensation
- Cholecystitis (infection of gallbladder)
- Fatigue (feeling of tiredness)
- Headache (pain in head)
- Hepatic enzyme increased
male:
- Abdominal discomfort
- Weight decreased
- Bilirubin conjugated increased
- Blood bilirubin increased
- White blood cell count increased
- Fatigue (feeling of tiredness)
- Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
- Pain
- Platelet count decreased
- Swelling
What are the common drug interactions of Vitamin E and Exjade, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Blood urine present
- Protein urine present
- Abdominal pain
- Cholecystitis (infection of gallbladder)
- Hepatic enzyme increased
- Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
- Nausea (feeling of having an urge to vomit)
- Vomiting
10-19:
- Vomiting
- Diarrhoea
- Osteonecrosis (death of bone)
- Pain in extremity
- Viral infection
- Abdominal pain
- Blood urine present
- Cholecystitis (infection of gallbladder)
- Hepatic enzyme increased
- Nausea (feeling of having an urge to vomit)
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Abdominal pain
- Blood iron increased
- Burning sensation
- Diarrhoea
- Erythema (redness of the skin)
- Gastric disorder (disease of stomach)
- Gastrointestinal tract irritation
- Headache (pain in head)
- Hypersensitivity
- Influenza like illness
60+:
- Abdominal discomfort
- Alanine aminotransferase increased
- Blood iron increased
- Death
- Diarrhoea
- Fall
- Pain in extremity
- Pelvic fracture
- Bilirubin conjugated increased
- Blood bilirubin increased
What are the existing conditions these people have? *
- Blood Iron Increased: 10 people, 29.41%
- Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 4 people, 11.76%
- Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 2 people, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Vitamin e and Exjade?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Vitamin e and Exjade:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Vitamin e:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Exjade:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Vitamin e and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Exjade and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Díaz-García JD, Gallegos-Villalobos A, Gonzalez-Espinoza L, Sanchez-Ni?o MD, Villarrubia J, Ortiz A, "Deferasirox nephrotoxicity [mdash] the knowns and unknowns", Nature reviews nephrology, 2014 Oct .
- Riva A, "Comment on: A record number of fatalities in many categories of patients treated with deferasirox: loopholes in regulatory and marketing procedures undermine patient safety and misguide public funds?", Expert opinion on drug safety, 2013 Sep .
- Riva A, "Deferasirox's toxicity", The Lancet, 2013 Jul .
- Kontoghiorghes GJ, "Turning a blind eye to deferasirox's toxicity?", The Lancet, 2013 Apr .
- Kontoghiorghes GJ, "A record number of fatalities in many categories of patients treated with deferasirox: loopholes in regulatory and marketing procedures undermine patient safety and misguide public funds?", Taylor & Francis, 2013 Jan .
- Díaz-García JD, Gallegos-Villalobos A, Gonzalez-Espinoza L, Sanchez-Ni?o MD, Villarrubia J, Ortiz A, "Deferasirox nephrotoxicity [mdash] the knowns and unknowns", Nature reviews nephrology, 2014 Oct .
- Riva A, "Comment on: A record number of fatalities in many categories of patients treated with deferasirox: loopholes in regulatory and marketing procedures undermine patient safety and misguide public funds?", Expert opinion on drug safety, 2013 Sep .
- Riva A, "Deferasirox's toxicity", The Lancet, 2013 Jul .
- Kontoghiorghes GJ, "Turning a blind eye to deferasirox's toxicity?", The Lancet, 2013 Apr .
- Kontoghiorghes GJ, "A record number of fatalities in many categories of patients treated with deferasirox: loopholes in regulatory and marketing procedures undermine patient safety and misguide public funds?", Taylor & Francis, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on tocopherols and tocotrienols and deferasirox (the active ingredients of Vitamin e and Exjade, respectively), and Vitamin e and Exjade (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Methotrexate Sodium and Sleep Apnoea Syndrome for Women aged 60+ - 2 seconds ago
- Methotrexate Sodium and Sleep Apnea Syndrome for Women aged 60+ - 3 seconds ago
- Docetaxel and Hypokalemia for Men aged 40-49 - 6 seconds ago
- Docetaxel and Hypokalemic Syndrome for Men aged 40-49 - 6 seconds ago
- Docetaxel and Hypokalaemic Syndrome for Men aged 40-49 - 6 seconds ago
- Docetaxel and Hypopotassemia for Men aged 40-49 - 6 seconds ago
- Docetaxel and Hypokalaemia for Men aged 40-49 - 7 seconds ago
- Docetaxel and Potassium - Low for Men aged 40-49 - 7 seconds ago
- Docetaxel and Low Blood Potassium for Men aged 40-49 - 7 seconds ago
- Lamictal and Blind for Women aged 50-59 - 13 seconds ago