Vitamin e and Levemir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vitamin e (tocopherols and tocotrienols) and Levemir (insulin detemir recombinant). Common drug interactions include drug intolerance among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Vitamin e and Levemir. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Vitamin e?

Vitamin e has active ingredients of tocopherols and tocotrienols. It is often used in vitamin supplementation. eHealthMe is studying from 42,279 Vitamin e users. Check the latest studies of Vitamin e.

What is Levemir?

Levemir has active ingredients of insulin detemir recombinant. It is often used in diabetes. eHealthMe is studying from 13,850 Levemir users. Check the latest studies of Levemir.



On Jul, 19, 2026

40 people who take Vitamin e and Levemir together, and have interactions are studied.

Vitamin e and Levemir drug interactions.

What are the common drug interactions of Vitamin E and Levemir, by gender? *:

female:

  1. Drug intolerance (drug sensitivity)
  2. Dry mouth
  3. Ear disorder
  4. Ear infection
  5. Fatigue (feeling of tiredness)
  6. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  7. Glycosylated haemoglobin increased
  8. Haematuria (presence of blood in urine)
  9. Headache (pain in head)
  10. Hearing impaired

male:

  1. Drug ineffective
  2. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
  3. Back pain
  4. Blood pressure decreased
  5. Blood pressure increased
  6. Cardiac arrest
  7. Carotid artery occlusion (artery blockage)
  8. Cerebral infarction (less blood supply to brain resulting tissue damage)
  9. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  10. Constipation

What are the common drug interactions of Vitamin E and Levemir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Blood creatinine increased
  2. Ear disorder
  3. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
  4. Renal injury (kidney injury)

20-29:

  1. Gastrointestinal motility disorder (abnormal intestinal contractions)
  2. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
  3. Menstrual disorder (disease of menstrual cycle)

30-39:

  1. Asthenia (weakness)
  2. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  3. Cough
  4. Dizziness
  5. Hypertension (high blood pressure)
  6. Infection
  7. Interstitial lung disease
  8. Muscular weakness (muscle weakness)
  9. Nasopharyngitis (inflammation of the nasopharynx)

40-49:

  1. Anaemia (lack of blood)
  2. Bone pain
  3. Drug ineffective
  4. Dyspnoea (difficult or laboured respiration)
  5. Ear infection
  6. Hysterectomy
  7. Pruritus (severe itching of the skin)
  8. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  9. Sinusitis (inflammation of sinus)
  10. Splenomegaly (enlargement of spleen)

50-59:

  1. Pain in extremity
  2. Pneumonia
  3. Cardiac arrest
  4. Concussion (short loss of normal brain function in response to a head injury)
  5. Dizziness
  6. Fall
  7. Hypervitaminosis d (state of vitamin d toxicity)
  8. Hypoglycaemia (deficiency of glucose in the bloodstream)
  9. Hypotension (abnormally low blood pressure)
  10. Insomnia (sleeplessness)

60+:

  1. Visual impairment
  2. Fall
  3. Limb deformity (functional disability of leg)
  4. Muscle spasms (muscle contraction)
  5. Sensory loss (senses loss)
  6. Sinus congestion (blockage of sinus)
  7. Vision blurred
  8. Weight decreased
  9. Adverse drug reaction
  10. Cardiomyopathy (weakening of the heart muscle)

What are the existing conditions these people have? *

  1. High Blood Pressure: 7 people, 17.50%
  2. Insomnia (sleeplessness): 4 people, 10.00%
  3. Cystic Fibrosis (disease of the secretary glands): 4 people, 10.00%
  4. Depression: 4 people, 10.00%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 10.00%
  6. High Blood Cholesterol: 4 people, 10.00%
  7. Pain: 4 people, 10.00%
  8. Type 2 Diabetes: 3 people, 7.50%
  9. Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 7.50%
  10. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 7.50%

* Approximation only. Some reports may have incomplete information.

Do you take Vitamin e and Levemir?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vitamin e and Levemir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vitamin e:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Levemir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vitamin e and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Levemir and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on tocopherols and tocotrienols and insulin detemir recombinant (the active ingredients of Vitamin e and Levemir, respectively), and Vitamin e and Levemir (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: