Vitamin e and Topicort drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vitamin e (tocopherols and tocotrienols) and Topicort (desoximetasone). Common drug interactions include swelling among females and crohn's disease among males.

The phase IV clinical study analyzes what interactions people have when they take Vitamin e and Topicort. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Vitamin e?

Vitamin e has active ingredients of tocopherols and tocotrienols. It is often used in vitamin supplementation. eHealthMe is studying from 42,279 Vitamin e users. Check the latest studies of Vitamin e.

What is Topicort?

Topicort has active ingredients of desoximetasone. eHealthMe is studying from 3,423 Topicort users. Check the latest studies of Topicort.



On Jul, 10, 2026

29 people who take Vitamin e and Topicort together, and have interactions are studied.

Vitamin e and Topicort drug interactions.

What are the common drug interactions of Vitamin E and Topicort, by gender? *:

female:

  1. Swelling
  2. Vomiting
  3. Drug hypersensitivity
  4. Respiratory disorder (respiratory disease)
  5. Sleep disorder
  6. Infusion related reaction
  7. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  8. Dizziness
  9. Dry mouth
  10. Inflammation

male:

  1. Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
  2. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  3. Device dislocation
  4. Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
  5. Diverticulum intestinal haemorrhagic (a pouch that is attached to the first part of the small intestine with bleeding)
  6. Fall
  7. Femur fracture
  8. Fracture displacement
  9. Gastritis (inflammation of stomach)
  10. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

What are the common drug interactions of Vitamin E and Topicort, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Mobility decreased (ability to move is reduced)
  2. Muscular weakness (muscle weakness)
  3. Dyspnoea (difficult or laboured respiration)
  4. Joint swelling
  5. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  6. Pain
  7. Injury
  8. Lower respiratory tract infection
  9. Sinusitis (inflammation of sinus)
  10. Maternal exposure during pregnancy (use of substance during pregnancy)

50-59:

n/a

60+:

  1. Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
  2. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  3. Skin irritation
  4. Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
  5. Large intestine perforation (hole in large intestine)
  6. Hypoxia (low oxygen in tissues)
  7. Pericardial effusion (fluid around the heart)
  8. Pleural effusion (water on the lungs)
  9. Anorectal discomfort
  10. Fungal infection

What are the existing conditions these people have? *

  1. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 18 people, 62.07%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 18 people, 62.07%
  3. Psoriasis (immune-mediated disease that affects the skin): 17 people, 58.62%
  4. Ankylosing Spondylitis (type of arthritis affecting the spine): 16 people, 55.17%
  5. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 16 people, 55.17%
  6. Arthritis (form of joint disorder that involves inflammation of one or more joints): 6 people, 20.69%
  7. Pain: 6 people, 20.69%
  8. Fever: 4 people, 13.79%
  9. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 4 people, 13.79%
  10. Stress And Anxiety: 3 people, 10.34%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vitamin e and Topicort:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vitamin e:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Topicort:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vitamin e and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Topicort and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on tocopherols and tocotrienols and desoximetasone (the active ingredients of Vitamin e and Topicort, respectively), and Vitamin e and Topicort (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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