Vitamins and Novalgin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vitamins (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e) and Novalgin (metamizole). Common drug interactions include muscle spasms among females and toxic epidermal necrolysis among males.

The phase IV clinical study analyzes what interactions people have when they take Vitamins and Novalgin. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Vitamins?

Vitamins has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 122,458 Vitamins users. Check the latest studies of Vitamins.

What is Novalgin?

Novalgin has active ingredients of metamizole. It is often used in pain. eHealthMe is studying from 10,177 Novalgin users. Check the latest studies of Novalgin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

38 people who take Vitamins and Novalgin together, and have interactions are studied.

Vitamins and Novalgin drug interactions.

What are the common drug interactions of Vitamins and Novalgin, by gender? *:

female:

Muscle spasms (muscle contraction)
Pain in extremity
Pancreatic neoplasm (pancreatic tumour)
Parosmia (distortion of the sense of smell, as in smelling odours that are not present)
Periarthritis (inflammation of the external coats of an artery and of the tissues around the artery)
Pruritus (severe itching of the skin)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Vomiting
Depressed mood
Leukopenia (less number of white blood cells in blood)

male:

Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Blood alkaline phosphatase increased
Diarrhoea
Gamma-glutamyltransferase increased
Hepatic enzyme increased
Cardiac failure
Sepsis (a severe blood infection that can lead to organ failure and death)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Erythema (redness of the skin)

What are the common drug interactions of Vitamins and Novalgin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Hepatic enzyme increased

10-19:

n/a

20-29:

Abdominal distension
Abdominal pain
Drug ineffective
Haemorrhagic anaemia (anaemia due to excessive bleeding)
Intra-abdominal haemorrhage (intra-abdominal bleeding)

30-39:

Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Lip disorder (disease of lip)
Mucosal erosion (peeling off of mucous membrane)
Pruritus (severe itching of the skin)
Pyrexia (fever)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)

40-49:

Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Pneumonia
Cardiac failure
Sepsis (a severe blood infection that can lead to organ failure and death)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Angioedema (rapid swelling of the dermis)
Ascites (accumulation of fluid in the abdominal cavity)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Completed suicide (act of taking one's own life)

50-59:

Depressed mood
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Metastases to lung (cancer spreads to lung)
Abdominal pain upper
Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood potassium increased
Breast pain

60+:

Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Pruritus (severe itching of the skin)
Mucosal inflammation (infection of mucous membrane)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pneumonia
Urinary hesitation (difficulty in beginning the flow of urine)
Basal ganglia haemorrhage (bleeding from blood vessels in an area of the brain responsible for body movements)
Lymphocyte percentage decreased
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Pyrexia (fever)

What are the existing conditions these people have? *

Heart Disease: 12 people, 31.58%
Diabetes: 11 people, 28.95%
Infection: 11 people, 28.95%
High Blood Pressure: 10 people, 26.32%
Oedema (fluid collection in tissue): 10 people, 26.32%
Depression: 10 people, 26.32%
Fungal Infection: 10 people, 26.32%
Nausea (feeling of having an urge to vomit): 9 people, 23.68%
Urinary Tract Infection: 9 people, 23.68%
Sedation: 9 people, 23.68%

* Approximation only. Some reports may have incomplete information.

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