Vitamins and Plendil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vitamins (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e) and Plendil (felodipine). Common drug interactions include oedema peripheral among females and oedema peripheral among males.

The phase IV clinical study analyzes what interactions people have when they take Vitamins and Plendil. It is created by eHealthMe based on reports of 94 people who take the same drugs from the FDA, and is updated regularly.

What is Vitamins?

Vitamins has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 122,456 Vitamins users. Check the latest studies of Vitamins.

What is Plendil?

Plendil has active ingredients of felodipine. It is often used in high blood pressure. eHealthMe is studying from 4,990 Plendil users. Check the latest studies of Plendil.

On Jul, 17, 2026

94 people who take Vitamins and Plendil together, and have interactions are studied.

What are the common drug interactions of Vitamins and Plendil, by gender? *:

female:

Oedema peripheral (superficial swelling)
Injury
Burning sensation
Peripheral coldness
Skin discolouration (change of skin colour)
Anxiety
Blood cholesterol increased
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Erythema (redness of the skin)
Fall

male:

Oedema peripheral (superficial swelling)
Arthralgia (joint pain)
Bladder cancer
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiomyopathy (weakening of the heart muscle)
Decreased interest
Dyslipidaemia (abnormal amount of lipids)
Ejection fraction decreased (systolic heart failure)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Herpes zoster

What are the common drug interactions of Vitamins and Plendil, by age (0-1 to 60+)? *:

0-1:

Aortic valve stenosis (narrowing of the aortic valve)
Headache (pain in head)
Injection site discolouration
Nervousness
Scratch

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Arthralgia (joint pain)
Joint stiffness
Mobility decreased (ability to move is reduced)
Myalgia (muscle pain)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Oedema peripheral (superficial swelling)
Pain in extremity

40-49:

Ascites (accumulation of fluid in the abdominal cavity)
Atelectasis (partial or complete collapse of the lung)
Biliary cirrhosis primary (primary biliary cirrhosis (pbc) is a long-term liver disease that damages the small bile ducts in the liver. the build-up of bile damages the liver)
Cardiomegaly (increased size of heart than normal)
Coagulopathy (blood's ability to clot is impaired)
Dehydration (dryness resulting from the removal of water)
Disease recurrence
Drug ineffective
Encephalopathy (functioning of the brain is affected by some agent or condition)
Haemothorax (collection of blood in the pleural space (the space between the lungs and the walls of the chest))

50-59:

Emotional distress
Erythema (redness of the skin)
Injury
Joint range of motion decreased (disease of joint movement)
Joint stiffness
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Oedema peripheral (superficial swelling)
Pain
Peripheral coldness
Pruritus (severe itching of the skin)

60+:

Arthralgia (joint pain)
Oedema peripheral (superficial swelling)
Blood cholesterol increased
Fall
Infection
Oedema (fluid collection in tissue)
Pruritus generalised (generalized itching)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Anaemia (lack of blood)
Anaemia postoperative

What are the existing conditions these people have? *

Bone Disorder: 17 people, 18.09%
Headache (pain in head): 14 people, 14.89%
Multiple Myeloma (cancer of the plasma cells): 9 people, 9.57%
Indigestion: 9 people, 9.57%
Stress And Anxiety: 7 people, 7.45%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 6.38%
Insomnia (sleeplessness): 6 people, 6.38%
Sleep Apnea Syndrome: 5 people, 5.32%
Nuclear Magnetic Resonance Imaging Brain: 5 people, 5.32%
High Blood Cholesterol: 5 people, 5.32%

* Approximation only. Some reports may have incomplete information.

Do you take Vitamins and Plendil?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously