Vivelle and Valium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vivelle (estradiol) and Valium (diazepam). Common drug interactions include drug ineffective among females.

The phase IV clinical study analyzes what interactions people have when they take Vivelle and Valium. It is created by eHealthMe based on reports of 90 people who take the same drugs from the FDA, and is updated regularly.

What is Vivelle?

Vivelle has active ingredients of estradiol. It is often used in hormone replacement therapy. eHealthMe is studying from 6,624 Vivelle users. Check the latest studies of Vivelle.

What is Valium?

Valium has active ingredients of diazepam. It is often used in stress and anxiety. eHealthMe is studying from 48,647 Valium users. Check the latest studies of Valium.

On Jul, 17, 2026

90 people who take Vivelle and Valium together, and have interactions are studied.

What are the common drug interactions of Vivelle and Valium, by gender? *:

female:

Drug ineffective
Pain
Fatigue (feeling of tiredness)
Hyperhidrosis (abnormally increased sweating)
Hypertension (high blood pressure)
Skin burning sensation
Vision blurred
Arthralgia (joint pain)
Dyspnoea (difficult or laboured respiration)
Gastrointestinal disorder (functional problems of gastrointestinal tract)

male:

n/a

What are the common drug interactions of Vivelle and Valium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Cystitis interstitial (unknown cause characterized by bladder pain)
Drug ineffective

40-49:

Drug ineffective
Back pain
Bipolar ii disorder (characterized by at least one episode of hypomania and at least one episode of major depression)
General physical health deterioration (weak health status)
Pain
Suicidal ideation
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Borderline personality disorder
Cervical spinal stenosis (narrowing of the spinal canal in the neck)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

50-59:

Facial pain
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Heart rate irregular
Knee arthroplasty
Uveitis (inflammation of the uvea)
Weight increased
Abdominal discomfort
Affect lability (emotional incontinence)
Anaemia (lack of blood)
Blood glucose increased

60+:

Malaise (a feeling of general discomfort or uneasiness)
Asthenia (weakness)
Influenza like illness
Pain
Renal failure (kidney dysfunction)
Small intestinal obstruction (blockage in small intestine)
Drug dependence
Abdominal pain upper
Abnormal behaviour
Blood calcium decreased

What are the existing conditions these people have? *

Pain: 16 people, 17.78%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 15 people, 16.67%
Insomnia (sleeplessness): 14 people, 15.56%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 11 people, 12.22%
Sleep Disorder: 9 people, 10.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 9 people, 10.00%
Nausea (feeling of having an urge to vomit): 8 people, 8.89%
Infection: 7 people, 7.78%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 7 people, 7.78%
Hypoaesthesia (reduced sense of touch or sensation): 6 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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