Voltaren and Metrogel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Voltaren (diclofenac sodium) and Metrogel (metronidazole). Common drug interactions include euphoric mood among females and atrial fibrillation among males.

The phase IV clinical study analyzes what interactions people have when they take Voltaren and Metrogel. It is created by eHealthMe based on reports of 79 people who take the same drugs from the FDA, and is updated regularly.

What is Voltaren?

Voltaren has active ingredients of diclofenac sodium. It is often used in arthritis. eHealthMe is studying from 82,346 Voltaren users. Check the latest studies of Voltaren.

What is Metrogel?

Metrogel has active ingredients of metronidazole. It is often used in rosacea. eHealthMe is studying from 2,819 Metrogel users. Check the latest studies of Metrogel.

On Jul, 17, 2026

79 people who take Voltaren and Metrogel together, and have interactions are studied.

Voltaren and Metrogel drug interactions.

What are the common drug interactions of Voltaren and Metrogel, by gender? *:

female:

Euphoric mood (excessively happy but may become angry or irritable)
Fall
Febrile neutropenia (fever with reduced white blood cells)
Memory impairment
Peripheral swelling
Type 2 diabetes mellitus
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)

male:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Device occlusion
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Genital discomfort
Glucose urine present
Hypotension (abnormally low blood pressure)
Joint dislocation (a joint position is changed from normal position)
Mobility decreased (ability to move is reduced)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Palpitations (feelings or sensations that your heart is pounding or racing)

What are the common drug interactions of Voltaren and Metrogel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anxiety
Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
Fibromyalgia (a long-term condition which causes pain all over the body)
Mania (a state of abnormally elevated or irritable mood)
Neuropathy peripheral (surface nerve damage)
Renal failure (kidney dysfunction)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Chronic kidney disease
Device occlusion

40-49:

Drug ineffective
Nausea (feeling of having an urge to vomit)
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Epistaxis (bleed from the nose)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Neck injury
Oesophageal pain
Oropharyngeal pain
Road traffic accident
Sinus disorder (disease of sinus)

50-59:

Peripheral swelling
Type 2 diabetes mellitus
Viral infection
Abdominal distension
Chronic kidney disease
Drug intolerance (drug sensitivity)
Exostosis (formation of new bone on the surface of a bone)
Gait disturbance
Headache (pain in head)
Plantar fasciitis (painful inflammatory process of the plantar fascia)

60+:

Urinary tract infection
Fatigue (feeling of tiredness)
Mobility decreased (ability to move is reduced)
Nausea (feeling of having an urge to vomit)
Abdominal discomfort
Abdominal pain
Abdominal pain lower
Acne (skin problems that cause pimples)
Arthralgia (joint pain)
Body temperature decreased

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 19 people, 24.05%
Pain: 19 people, 24.05%
Stress And Anxiety: 14 people, 17.72%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 13 people, 16.46%
Emotional Disorder: 12 people, 15.19%
Fibromyalgia (a long-term condition which causes pain all over the body): 11 people, 13.92%
Urinary Tract Infection: 11 people, 13.92%
High Blood Pressure: 10 people, 12.66%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 10.13%
Muscle Spasms (muscle contraction): 8 people, 10.13%

* Approximation only. Some reports may have incomplete information.

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