Voriconazole and Kalydeco drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Voriconazole (voriconazole) and Kalydeco (ivacaftor). Common drug interactions include infective pulmonary exacerbation of cystic fibrosis among females and infective pulmonary exacerbation of cystic fibrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Voriconazole and Kalydeco. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Voriconazole?

Voriconazole has active ingredients of voriconazole. It is often used in aspergillosis. eHealthMe is studying from 21,706 Voriconazole users. Check the latest studies of Voriconazole.

What is Kalydeco?

Kalydeco has active ingredients of ivacaftor. eHealthMe is studying from 6,652 Kalydeco users. Check the latest studies of Kalydeco.

On Jul, 06, 2026

27 people who take Voriconazole and Kalydeco together, and have interactions are studied.

Voriconazole and Kalydeco drug interactions.

What are the common drug interactions of Voriconazole and Kalydeco, by gender? *:

female:

Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Lung disorder (lung disease)
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Infection
Contusion (a type of hematoma of tissue in which capillaries)
Pneumonia
Skin discolouration (change of skin colour)
Vascular purpura (haemorrhages in the skin and mucous membranes that result in the appearance of purplish spots or patches)

male:

Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Liver injury
Surgery
Transaminases increased
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Depressed mood
Fungal infection
Lethargy (tiredness)
Liver disorder (liver diseases)
Chest pain

What are the common drug interactions of Voriconazole and Kalydeco, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Contusion (a type of hematoma of tissue in which capillaries)
Pneumonia
Skin discolouration (change of skin colour)
Vascular purpura (haemorrhages in the skin and mucous membranes that result in the appearance of purplish spots or patches)
Liver disorder (liver diseases)
Pulmonary function test decreased
Benign intracranial hypertension (benign intracranial hypertension (bih) is a headache syndrome)
Chest pain

20-29:

Liver injury
Transaminases increased
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Anaphylactic reaction (serious allergic reaction)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain)
Lip swelling

30-39:

Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)

40-49:

Fungal infection
Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)

50-59:

Infection

60+:

n/a

What are the existing conditions these people have? *

Cystic Fibrosis (disease of the secretary glands): 26 people, 96.30%
Bronchitis Fungal (inflammation of the mucous membrane in the bronchial tubes due to fungal infection): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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