Voriconazole and Pemetrexed drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Voriconazole (voriconazole) and Pemetrexed (pemetrexed). Common drug interactions include abdominal discomfort among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Voriconazole and Pemetrexed. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Voriconazole?

Voriconazole has active ingredients of voriconazole. It is often used in aspergillosis. eHealthMe is studying from 21,706 Voriconazole users. Check the latest studies of Voriconazole.

What is Pemetrexed?

Pemetrexed has active ingredients of pemetrexed. eHealthMe is studying from 17,491 Pemetrexed users. Check the latest studies of Pemetrexed.



On Aug, 02, 2026

22 people who take Voriconazole and Pemetrexed together, and have interactions are studied.

Voriconazole and Pemetrexed drug interactions.

What are the common drug interactions of Voriconazole and Pemetrexed, by gender? *:

female:

  1. Abdominal discomfort
  2. Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
  3. Coagulopathy (blood's ability to clot is impaired)
  4. Disseminated intravascular coagulation (systemic activation of blood coagulation)
  5. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  6. Respiratory failure (inadequate gas exchange by the respiratory system)
  7. Septic shock (shock due to blood infection)
  8. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
  9. Disease progression
  10. Interstitial lung disease

male:

  1. Pneumonia
  2. Respiratory failure (inadequate gas exchange by the respiratory system)
  3. Malignant neoplasm progression (cancer tumour came back)
  4. Hypersensitivity pneumonitis
  5. Adrenal disorder
  6. Anaemia (lack of blood)
  7. Laryngeal pain
  8. Platelet count decreased
  9. Liver disorder (liver diseases)
  10. Lung disorder (lung disease)

What are the common drug interactions of Voriconazole and Pemetrexed, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Liver disorder (liver diseases)
  2. Lung disorder (lung disease)
  3. Interstitial lung disease
  4. Malignant neoplasm progression (cancer tumour came back)

50-59:

n/a

60+:

  1. Pneumonia
  2. Respiratory failure (inadequate gas exchange by the respiratory system)
  3. Disseminated intravascular coagulation (systemic activation of blood coagulation)
  4. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  5. Septic shock (shock due to blood infection)
  6. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
  7. Disease progression
  8. Interstitial lung disease
  9. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  10. Hypersensitivity pneumonitis

What are the existing conditions these people have? *

  1. Lung Adenocarcinoma (a form of non-small cell lung cancer): 11 people, 50.00%
  2. Productive Cough: 8 people, 36.36%
  3. Infection: 8 people, 36.36%
  4. High Blood Pressure: 6 people, 27.27%
  5. Herpes Zoster: 5 people, 22.73%
  6. Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection): 5 people, 22.73%
  7. Urination - Excessive Volume: 5 people, 22.73%
  8. Muscle Spasms (muscle contraction): 5 people, 22.73%
  9. Pain: 5 people, 22.73%
  10. Asthma: 5 people, 22.73%

* Approximation only. Some reports may have incomplete information.

Do you take Voriconazole and Pemetrexed?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Voriconazole and Pemetrexed:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Voriconazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pemetrexed:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Voriconazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pemetrexed and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on voriconazole and pemetrexed (the active ingredients of Voriconazole and Pemetrexed, respectively), and Voriconazole and Pemetrexed (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: