Votrient and Cardura drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Votrient (pazopanib hydrochloride) and Cardura (doxazosin mesylate). Common drug interactions include agitation among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Votrient and Cardura. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Votrient?

Votrient has active ingredients of pazopanib hydrochloride. It is often used in metastatic renal cell carcinoma. eHealthMe is studying from 25,347 Votrient users. Check the latest studies of Votrient.

What is Cardura?

Cardura has active ingredients of doxazosin mesylate. It is often used in high blood pressure. eHealthMe is studying from 20,379 Cardura users. Check the latest studies of Cardura.



On Jul, 11, 2026

22 people who take Votrient and Cardura together, and have interactions are studied.

Votrient and Cardura drug interactions.

What are the common drug interactions of Votrient and Cardura, by gender? *:

female:

  1. Agitation (state of anxiety or nervous excitement)
  2. Cerebral haemorrhage (bleeding within the brain)
  3. Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
  4. Confusional state
  5. Decreased appetite
  6. Eructation (release of gas from the digestive tract)
  7. Feeling cold
  8. Flatulence (flatus expelled through the anus)
  9. Hemianopia (blindness or reduction in vision in one half of the visual field due to damage of the optic pathways in the brain)
  10. Lethargy (tiredness)

male:

  1. Asthenia (weakness)
  2. Dysphonia (speech disorder attributable to a disorder of phonation)
  3. Weight decreased
  4. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  5. Dehydration (dryness resulting from the removal of water)
  6. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  7. Nausea (feeling of having an urge to vomit)
  8. Pain
  9. Rash
  10. Vomiting

What are the common drug interactions of Votrient and Cardura, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Asthenia (weakness)
  2. Dysphonia (speech disorder attributable to a disorder of phonation)
  3. Therapeutic response delayed (late preventive response)
  4. Vomiting
  5. Weight decreased
  6. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  7. Decreased appetite
  8. Dehydration (dryness resulting from the removal of water)
  9. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  10. Pain

What are the existing conditions these people have? *

  1. Renal Cell Carcinoma (a kidney cancer): 14 people, 63.64%
  2. Type 1 Diabetes: 3 people, 13.64%
  3. Neoplasm Malignant (cancer tumour): 3 people, 13.64%

* Approximation only. Some reports may have incomplete information.

Do you take Votrient and Cardura?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Votrient and Cardura:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Votrient:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cardura:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Votrient and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cardura and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on pazopanib hydrochloride and doxazosin mesylate (the active ingredients of Votrient and Cardura, respectively), and Votrient and Cardura (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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