Votrient and Folic acid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Votrient (pazopanib hydrochloride) and Folic acid (folic acid). Common drug interactions include pulmonary embolism among females and decreased appetite among males.

The phase IV clinical study analyzes what interactions people have when they take Votrient and Folic acid. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Votrient?

Votrient has active ingredients of pazopanib hydrochloride. It is often used in metastatic renal cell carcinoma. eHealthMe is studying from 25,347 Votrient users. Check the latest studies of Votrient.

What is Folic acid?

Folic acid has active ingredients of folic acid. It is often used in rheumatoid arthritis. eHealthMe is studying from 165,025 Folic acid users. Check the latest studies of Folic acid.

On Jul, 20, 2026

37 people who take Votrient and Folic acid together, and have interactions are studied.

Votrient and Folic acid drug interactions.

What are the common drug interactions of Votrient and Folic Acid, by gender? *:

female:

Pulmonary embolism (blockage of the main artery of the lung)
Renal failure (kidney dysfunction)
Sinusitis (inflammation of sinus)
Skin ulcer
Weight decreased
Weight increased
Death
Disease progression
Diarrhoea
Drug ineffective

male:

Decreased appetite
Fatigue (feeling of tiredness)
Eating disorder
Renal cancer (cancer of kidney)
Cardiac failure
Cardiogenic shock (inadequate circulation of blood)
Cardiotoxicity (damage to the heart muscle)
Confusional state
Dyspnoea (difficult or laboured respiration)
Ejection fraction decreased (systolic heart failure)

What are the common drug interactions of Votrient and Folic Acid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abortion spontaneous (naturally occurring miscarriage)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood alkaline phosphatase increased
Blood bilirubin increased
Breast cancer
Disease progression
Dissociative disorder
Hepatic failure (liver failure)

50-59:

Death
Disease progression
Dyspnoea exertional (breathlessness or shortness of breath)
Pneumonia
Pulmonary embolism (blockage of the main artery of the lung)
Sinusitis (inflammation of sinus)
Skin ulcer
Weight decreased
Weight increased

60+:

Drug ineffective
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Blindness
Dry mouth
Dyspepsia (indigestion)
Eating disorder
Renal cancer (cancer of kidney)
Cardiac failure
Cardiogenic shock (inadequate circulation of blood)

What are the existing conditions these people have? *

Renal Cell Carcinoma (a kidney cancer): 16 people, 43.24%
Sarcoma (rare cancers that develop in the muscle, bone, nerves, cartilage, tendons, blood vessels and the fatty and fibrous tissues): 3 people, 8.11%
High Blood Pressure: 3 people, 8.11%
Ovarian Cancer (cancer of ovary): 2 people, 5.41%
Malignant Soft Tissue Neoplasm (cancer tumour of soft tissue): 2 people, 5.41%
Lung Cancer - Non-Small Cell (lung cancer): 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

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