Vraylar and Keflex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vraylar (cariprazine hydrochloride) and Keflex (cephalexin). Common drug interactions include lymphadenitis among females.

The phase IV clinical study analyzes what interactions people have when they take Vraylar and Keflex. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Vraylar?

Vraylar has active ingredients of cariprazine hydrochloride. eHealthMe is studying from 6,136 Vraylar users. Check the latest studies of Vraylar.

What is Keflex?

Keflex has active ingredients of cephalexin. It is often used in infection. eHealthMe is studying from 15,844 Keflex users. Check the latest studies of Keflex.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

14 people who take Vraylar and Keflex together, and have interactions are studied.

What are the common drug interactions of Vraylar and Keflex, by gender? *:

female:

Lymphadenitis (inflammation or enlargement of a lymph node)
Ear infection
Bacterial infection
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Malaise (a feeling of general discomfort or uneasiness)
Psoriasis (immune-mediated disease that affects the skin)
Staphylococcal infection (an infection with staphylococcus bacteria)
Adverse drug reaction
Anxiety
Bipolar ii disorder (characterized by at least one episode of hypomania and at least one episode of major depression)

male:

n/a

What are the common drug interactions of Vraylar and Keflex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Sexual abuse
Sinusitis (inflammation of sinus)
Upper respiratory tract infection
Bacterial infection
Wound
Anal infection
Ear infection
Gallbladder disorder
Lymphadenitis (inflammation or enlargement of a lymph node)
Middle ear effusion (fluid in middle ear)

30-39:

Heart rate increased
Hypertension (high blood pressure)

40-49:

Chronic kidney disease

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 8 people, 57.14%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 14.29%
Nausea (feeling of having an urge to vomit): 2 people, 14.29%
Pain: 2 people, 14.29%
Depression: 2 people, 14.29%
Staphylococcal Infection (an infection with staphylococcus bacteria): 2 people, 14.29%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 7.14%
Constipation: 1 person, 7.14%
Bipolar Ii Disorder (characterized by at least one episode of hypomania and at least one episode of major depression): 1 person, 7.14%
Hypersensitivity: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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