Vraylar and Xeljanz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vraylar (cariprazine hydrochloride) and Xeljanz (tofacitinib citrate). Common drug interactions include infection among females and depression among males.

The phase IV clinical study analyzes what interactions people have when they take Vraylar and Xeljanz. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Vraylar?

Vraylar has active ingredients of cariprazine hydrochloride. eHealthMe is studying from 6,136 Vraylar users. Check the latest studies of Vraylar.

What is Xeljanz?

Xeljanz has active ingredients of tofacitinib citrate. It is often used in rheumatoid arthritis. eHealthMe is studying from 239,081 Xeljanz users. Check the latest studies of Xeljanz.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

19 people who take Vraylar and Xeljanz together, and have interactions are studied.

What are the common drug interactions of Vraylar and Xeljanz, by gender? *:

female:

Infection
Nasopharyngitis (inflammation of the nasopharynx)
Neck pain
Oropharyngeal pain
Paronychia (infection in the tissues adjacent to a nail on a finger or toe)
Shoulder operation
Anaemia (lack of blood)
Anxiety
Contusion (a type of hematoma of tissue in which capillaries)
Cough

male:

Depression
Memory impairment

What are the common drug interactions of Vraylar and Xeljanz, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Depression
Memory impairment

20-29:

n/a

30-39:

Psoriasis (immune-mediated disease that affects the skin)
Drug ineffective
Arthralgia (joint pain)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Infection
Nasopharyngitis (inflammation of the nasopharynx)
Neck pain
Oropharyngeal pain
Paronychia (infection in the tissues adjacent to a nail on a finger or toe)

40-49:

Decreased activity
Hypersensitivity
Pain
Shoulder operation
Anaemia (lack of blood)
Arthralgia (joint pain)
Fatigue (feeling of tiredness)
Haematochezia (passage of stools containing blood)
Nausea (feeling of having an urge to vomit)

50-59:

Oral mucosal exfoliation (removal of mucous membrane of mouth)
Upper respiratory tract infection
Contusion (a type of hematoma of tissue in which capillaries)
Cough
Dry mouth
Headache (pain in head)
Mouth ulceration (mouth ulcers)

60+:

Anxiety
Drug ineffective
Hip arthroplasty
Memory impairment
Panic attack

What are the existing conditions these people have? *

Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 10.53%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 5.26%
Infection: 1 person, 5.26%
Depression: 1 person, 5.26%
Bipolar Disorder (mood disorder): 1 person, 5.26%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Vraylar and Xeljanz?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously