Vumerity and Methotrexate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vumerity (diroximel fumarate) and Methotrexate (methotrexate sodium). Common drug interactions include dyspnoea among females.

The phase IV clinical study analyzes what interactions people have when they take Vumerity and Methotrexate. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Vumerity?

Vumerity has active ingredients of diroximel fumarate. eHealthMe is studying from 9,781 Vumerity users. Check the latest studies of Vumerity.

What is Methotrexate?

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. eHealthMe is studying from 604,313 Methotrexate users. Check the latest studies of Methotrexate.

On Aug, 01, 2026

15 people who take Vumerity and Methotrexate together, and have interactions are studied.

Vumerity and Methotrexate drug interactions.

What are the common drug interactions of Vumerity and Methotrexate, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Abdominal discomfort
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
Sinusitis (inflammation of sinus)
Throat irritation
Diarrhoea
Abdominal distension
Constipation
Hot flush (sudden feelings of heat)
Death

male:

n/a

What are the common drug interactions of Vumerity and Methotrexate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Contusion (a type of hematoma of tissue in which capillaries)
Dizziness
Emotional disorder
Fall
Feeding disorder (when children refuse to eat certain food groups)
Feeling cold
Hot flush (sudden feelings of heat)
Hypoaesthesia (reduced sense of touch or sensation)
Mood altered (changes in mood)
Morbid thoughts (serious thoughts)

60+:

Abdominal discomfort
Chest pain
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
Sinusitis (inflammation of sinus)
Throat irritation
Abdominal distension
Constipation
Diarrhoea
Death
Cough

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 15 people, 100.00%
Vitamin D Decreased: 2 people, 13.33%
Stress And Anxiety: 2 people, 13.33%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 13.33%
High Blood Cholesterol: 2 people, 13.33%
Depression: 2 people, 13.33%
Constipation: 2 people, 13.33%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 13.33%
Gait Disturbance: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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