Vx-950 and Zyrtec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vx-950 (telaprevir) and Zyrtec (cetirizine hydrochloride). Common drug interactions include hypotension among females and drug rash with eosinophilia and systemic symptoms among males.

The phase IV clinical study analyzes what interactions people have when they take Vx-950 and Zyrtec. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Vx-950?

Vx-950 has active ingredients of telaprevir. eHealthMe is studying from 9,465 Vx-950 users. Check the latest studies of Vx-950.

What is Zyrtec?

Zyrtec has active ingredients of cetirizine hydrochloride. It is often used in allergies. eHealthMe is studying from 114,619 Zyrtec users. Check the latest studies of Zyrtec.

On Jul, 06, 2026

37 people who take Vx-950 and Zyrtec together, and have interactions are studied.

What are the common drug interactions of Vx-950 and Zyrtec, by gender? *:

female:

Hypotension (abnormally low blood pressure)
Influenza like illness
Insomnia (sleeplessness)
Irritability
Lethargy (tiredness)
Mania (a state of abnormally elevated or irritable mood)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Muscular weakness (muscle weakness)
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Myalgia (muscle pain)

male:

Drug rash with eosinophilia and systemic symptoms (adverse drug reactions with rash)
Fatigue (feeling of tiredness)
Haemorrhoidal haemorrhage (bleeding from the haemorrhoids)
Rectal haemorrhage (bleeding from anus)
Sinusitis (inflammation of sinus)
Cerebral haemorrhage (bleeding within the brain)
Rash
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaemia (lack of blood)
Anal pruritus (anal itching)

What are the common drug interactions of Vx-950 and Zyrtec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Rash
Depression
Diarrhoea
Post-traumatic stress disorder
Pyrexia (fever)
Anorectal discomfort
Fatigue (feeling of tiredness)
Haemorrhoidal haemorrhage (bleeding from the haemorrhoids)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Mania (a state of abnormally elevated or irritable mood)

40-49:

Dizziness
Dysphagia (a condition in which swallowing is difficult or painful)
Ear discomfort
Gastroenteritis staphylococcal (inflammation of stomach and intestine caused by staphylococcal infection)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Lethargy (tiredness)
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Oedema peripheral (superficial swelling)

50-59:

Fatigue (feeling of tiredness)
Anaemia (lack of blood)
Drug rash with eosinophilia and systemic symptoms (adverse drug reactions with rash)
Nausea (feeling of having an urge to vomit)
Pruritus (severe itching of the skin)
Dysgeusia (disorder of the sense of taste)
Anal pruritus (anal itching)
Anorectal discomfort
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dry skin

60+:

Nausea (feeling of having an urge to vomit)
Pneumonia
Constipation
Diarrhoea
Dysgeusia (disorder of the sense of taste)
Eye haemorrhage (bleeding in the eye)
Fatigue (feeling of tiredness)
Haemorrhoidal haemorrhage (bleeding from the haemorrhoids)
Headache (pain in head)
Influenza like illness

What are the existing conditions these people have? *

Hepatitis C: 32 people, 86.49%
Insomnia (sleeplessness): 7 people, 18.92%
Seasonal Allergy (allergic condition due to certain season): 6 people, 16.22%
Herpes Simplex (herpes simplex is a common viral infection): 6 people, 16.22%
Erection Problems: 6 people, 16.22%
Rashes (redness): 5 people, 13.51%
Headache (pain in head): 3 people, 8.11%
High Blood Pressure: 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

Do you take Vx-950 and Zyrtec?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously