Vytorin and Acyclovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vytorin (ezetimibe; simvastatin) and Acyclovir (acyclovir). Common drug interactions include pain among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Vytorin and Acyclovir. It is created by eHealthMe based on reports of 93 people who take the same drugs from the FDA, and is updated regularly.

What is Vytorin?

Vytorin has active ingredients of ezetimibe; simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 20,084 Vytorin users. Check the latest studies of Vytorin.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.



On Jul, 17, 2026

93 people who take Vytorin and Acyclovir together, and have interactions are studied.

Vytorin and Acyclovir drug interactions.

What are the common drug interactions of Vytorin and Acyclovir, by gender? *:

female:

  1. Pain
  2. Vomiting
  3. Arthralgia (joint pain)
  4. Emotional disorder
  5. Oedema peripheral (superficial swelling)
  6. Back pain
  7. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  8. Hyperlipidaemia (presence of excess lipids in the blood)
  9. Injury
  10. Pyrexia (fever)

male:

  1. Diarrhoea
  2. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  3. Dyspnoea (difficult or laboured respiration)
  4. Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
  5. Anxiety
  6. Appetite disorder (abnormal eating habits)
  7. Arthralgia (joint pain)
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  9. Blood pressure fluctuation
  10. Bone disorder

What are the common drug interactions of Vytorin and Acyclovir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  2. Malaise (a feeling of general discomfort or uneasiness)
  3. Adverse event
  4. Vomiting
  5. Anxiety
  6. Appetite disorder (abnormal eating habits)
  7. Arthralgia (joint pain)
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  9. Asthenia (weakness)
  10. Back pain

50-59:

  1. Oedema peripheral (superficial swelling)
  2. Anxiety
  3. Arthralgia (joint pain)
  4. Bone pain
  5. Chest pain
  6. Colitis (inflammation of colon)
  7. Cytomegalovirus infection
  8. Drug ineffective
  9. Fatigue (feeling of tiredness)
  10. Headache (pain in head)

60+:

  1. Diarrhoea
  2. Dehydration (dryness resulting from the removal of water)
  3. Pneumonia
  4. Renal failure (kidney dysfunction)
  5. Vomiting
  6. Asthenia (weakness)
  7. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  8. Death
  9. Depression
  10. Diverticular perforation (serious gastrointestinal condition in which the intestine's walls are perforated)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 28 people, 30.11%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 12.90%
  3. Pain: 11 people, 11.83%
  4. Diabetes: 7 people, 7.53%
  5. Malignant Melanoma (skin cancer rises from melancytes): 6 people, 6.45%
  6. Sleep Disorder: 5 people, 5.38%
  7. Diarrhea: 5 people, 5.38%
  8. Depression: 5 people, 5.38%
  9. Blood Phosphorus Decreased: 5 people, 5.38%
  10. Arterial Disorder: 5 people, 5.38%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vytorin and Acyclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vytorin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Acyclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vytorin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Acyclovir and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ezetimibe; simvastatin and acyclovir (the active ingredients of Vytorin and Acyclovir, respectively), and Vytorin and Acyclovir (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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