Vyvanse and Gemfibrozil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vyvanse (lisdexamfetamine dimesylate) and Gemfibrozil (gemfibrozil). Common drug interactions include drug hypersensitivity among females and suicidal ideation among males.

The phase IV clinical study analyzes what interactions people have when they take Vyvanse and Gemfibrozil. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Vyvanse?

Vyvanse has active ingredients of lisdexamfetamine dimesylate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 35,868 Vyvanse users. Check the latest studies of Vyvanse.

What is Gemfibrozil?

Gemfibrozil has active ingredients of gemfibrozil. It is often used in high blood cholesterol. eHealthMe is studying from 18,213 Gemfibrozil users. Check the latest studies of Gemfibrozil.

On Jul, 11, 2026

19 people who take Vyvanse and Gemfibrozil together, and have interactions are studied.

Vyvanse and Gemfibrozil drug interactions.

What are the common drug interactions of Vyvanse and Gemfibrozil, by gender? *:

female:

Drug hypersensitivity
Oedema (fluid collection in tissue)
Weight decreased

male:

Suicidal ideation
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Tremor (trembling or shaking movements in one or more parts of your body)
Visual impairment
Blood creatinine increased
Blood iron decreased
Blood potassium decreased
Ear disorder
Colonoscopy
Confusional state

What are the common drug interactions of Vyvanse and Gemfibrozil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Constipation
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hypotension (abnormally low blood pressure)
Loss of consciousness
Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
Retinal detachment (a disorder of the eye in which the retina peels away from its underlying layer of support tissue)
Tremor (trembling or shaking movements in one or more parts of your body)

50-59:

Weight decreased
Blood iron decreased
Colonoscopy
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
Suicidal ideation
Surgery
Ulcer haemorrhage (bleeding ulcer)

60+:

Confusional state
Drug effect increased
Feeling hot
Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 14 people, 73.68%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 31.58%
Hypersensitivity: 4 people, 21.05%
Stress And Anxiety: 3 people, 15.79%
Pain: 3 people, 15.79%
Depression: 3 people, 15.79%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 15.79%
Back Pain: 2 people, 10.53%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 10.53%
High Blood Pressure: 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

Do you take Vyvanse and Gemfibrozil?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously