Welchol and Acyclovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Welchol (colesevelam hydrochloride) and Acyclovir (acyclovir). Common drug interactions include wrist fracture among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Welchol and Acyclovir. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Welchol?

Welchol has active ingredients of colesevelam hydrochloride. It is often used in high blood cholesterol. eHealthMe is studying from 11,309 Welchol users. Check the latest studies of Welchol.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 16, 2026

58 people who take Welchol and Acyclovir together, and have interactions are studied.

Welchol and Acyclovir drug interactions.

What are the common drug interactions of Welchol and Acyclovir, by gender? *:

female:

Wrist fracture
Chest discomfort
Nail bed disorder (disease of nail bed)
Skin discolouration (change of skin colour)
Tinnitus (a ringing in the ears)
Abdominal discomfort
Abdominal pain
Abnormal dreams
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Balance disorder

male:

Anxiety
Emotional distress
Depression
Fall
Fatigue (feeling of tiredness)
Femur fracture
Fracture pain
Glomerular filtration rate increased
Hip fracture
Hypertension (high blood pressure)

What are the common drug interactions of Welchol and Acyclovir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal pain
Abdominal pain upper
Cholecystitis chronic (long lasting infection of gallbladder)
Gallbladder injury
Nausea (feeling of having an urge to vomit)
Pain

20-29:

n/a

30-39:

n/a

40-49:

Emotional distress
Fatigue (feeling of tiredness)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Pain
Renal impairment (severely reduced kidney function)
Drug intolerance (drug sensitivity)
Faeces discoloured
Muscular weakness (muscle weakness)

50-59:

Chronic kidney disease
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Blood creatinine increased
Emotional distress
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Pain
Renal cyst (kidney cyst)
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)

60+:

Fatigue (feeling of tiredness)
Anxiety
Osteoporosis (bones weak and more likely to break)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pruritus (severe itching of the skin)
Wrist fracture
Haemoglobin decreased
Joint swelling
Neuropathy peripheral (surface nerve damage)
Peripheral swelling

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 35 people, 60.34%
Hiv Infection: 6 people, 10.34%

* Approximation only. Some reports may have incomplete information.

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