Welchol and Combivent drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Welchol (colesevelam hydrochloride) and Combivent (albuterol sulfate; ipratropium bromide). Common drug interactions include renal failure among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Welchol and Combivent. It is created by eHealthMe based on reports of 75 people who take the same drugs from the FDA, and is updated regularly.

What is Welchol?

Welchol has active ingredients of colesevelam hydrochloride. It is often used in high blood cholesterol. eHealthMe is studying from 11,309 Welchol users. Check the latest studies of Welchol.

What is Combivent?

Combivent has active ingredients of albuterol sulfate; ipratropium bromide. It is often used in asthma. eHealthMe is studying from 35,341 Combivent users. Check the latest studies of Combivent.



On Jul, 12, 2026

75 people who take Welchol and Combivent together, and have interactions are studied.

Welchol and Combivent drug interactions.

What are the common drug interactions of Welchol and Combivent, by gender? *:

female:

  1. Renal failure (kidney dysfunction)
  2. Abdominal pain
  3. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  4. Depression
  5. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  6. Hypoxia (low oxygen in tissues)
  7. Urinary tract infection
  8. Wheezing (a high-pitched whistling sound made while you breath)
  9. Bone pain
  10. Cardiac failure congestive

male:

  1. Dyspnoea (difficult or laboured respiration)
  2. Cardiac disorder
  3. Oesophageal disorder (disease of oesophagus)
  4. Nausea (feeling of having an urge to vomit)
  5. Disability
  6. Pelvic fracture
  7. Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
  8. Fall
  9. Myalgia (muscle pain)
  10. Allergic sinusitis

What are the common drug interactions of Welchol and Combivent, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Petit mal epilepsy (absence seizure)
  2. Syncope (loss of consciousness with an inability to maintain postural tone)

20-29:

n/a

30-39:

n/a

40-49:

  1. Dyspnoea (difficult or laboured respiration)
  2. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  3. Muscle spasms (muscle contraction)
  4. Oedema (fluid collection in tissue)
  5. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  6. Pneumonia
  7. Renal failure acute (rapid kidney dysfunction)
  8. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  9. Urinary tract infection

50-59:

  1. Cervical radiculopathy (disturbance of nerve function that causes pain in the upper body)
  2. Chest pain
  3. Confusional state
  4. Cystitis (inflammation of the wall of the bladder)
  5. Cytomegalovirus infection
  6. Depression
  7. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  8. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
  9. Dizziness
  10. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)

60+:

  1. Rash
  2. Balance disorder
  3. Chest pain
  4. Haemorrhagic anaemia (anaemia due to excessive bleeding)
  5. Chronic kidney disease
  6. Drug ineffective
  7. Nephrogenic anaemia (anaemia due to kidney disease)
  8. Cardiac failure congestive
  9. Constipation
  10. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 16.00%
  2. Cardiac Disorder: 11 people, 14.67%
  3. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 11 people, 14.67%
  4. Diabetes: 10 people, 13.33%
  5. Nausea (feeling of having an urge to vomit): 10 people, 13.33%
  6. Blood Pressure Abnormal: 9 people, 12.00%
  7. Chest Pain: 9 people, 12.00%
  8. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 9 people, 12.00%
  9. Stress And Anxiety: 9 people, 12.00%
  10. Fluid Retention (an abnormal accumulation of fluid in the blood): 9 people, 12.00%

* Approximation only. Some reports may have incomplete information.

Do you take Welchol and Combivent?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Welchol and Combivent:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Welchol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Combivent:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Welchol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Combivent and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on colesevelam hydrochloride and albuterol sulfate; ipratropium bromide (the active ingredients of Welchol and Combivent, respectively), and Welchol and Combivent (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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