Welchol and Levothroid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Welchol (colesevelam hydrochloride) and Levothroid (levothyroxine sodium). Common drug interactions include rheumatoid arthritis among females and chest pain among males.

The phase IV clinical study analyzes what interactions people have when they take Welchol and Levothroid. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Welchol?

Welchol has active ingredients of colesevelam hydrochloride. It is often used in high blood cholesterol. eHealthMe is studying from 11,309 Welchol users. Check the latest studies of Welchol.

What is Levothroid?

Levothroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 8,974 Levothroid users. Check the latest studies of Levothroid.

On Jul, 19, 2026

25 people who take Welchol and Levothroid together, and have interactions are studied.

Welchol and Levothroid drug interactions.

What are the common drug interactions of Welchol and Levothroid, by gender? *:

female:

Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Sepsis (a severe blood infection that can lead to organ failure and death)
Septic shock (shock due to blood infection)
Sinusitis (inflammation of sinus)
Skin disorder (skin disease)
Splenomegaly (enlargement of spleen)
Blood creatinine increased
Cardiac failure congestive
Death
Proteinuria (presence of protein in the urine)

male:

Chest pain
Death
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Hypotension (abnormally low blood pressure)
Multi-organ failure (multisystem organ failure)
Myalgia (muscle pain)
Renal failure (kidney dysfunction)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Back pain
Blindness

What are the common drug interactions of Welchol and Levothroid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Death
Back pain
Blindness
Chest pain
Fall
Pneumonia
Arrhythmia (irregular heartbeat)
Asthenia (weakness)
Blood potassium decreased
Cardiac arrest

60+:

Blood pressure increased
Chest pain
Cardiac failure congestive
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Death
Drug ineffective
Heart rate irregular
Hyperbilirubinaemia (excess of bilirubin in the blood)
Hypokalaemia (low potassium)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)

What are the existing conditions these people have? *

High Blood Pressure: 9 people, 36.00%
Pain: 4 people, 16.00%
Diabetes: 4 people, 16.00%
Depression: 4 people, 16.00%
Upper Respiratory Tract Infection: 3 people, 12.00%
Swelling: 3 people, 12.00%
Pneumonia: 3 people, 12.00%
Pain In Extremity: 3 people, 12.00%
Infection: 3 people, 12.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 12.00%

* Approximation only. Some reports may have incomplete information.

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