Eliquis and Wellbutrin sr drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Eliquis (apixaban) and Wellbutrin sr (bupropion hydrochloride). Common drug interactions include death among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Eliquis and Wellbutrin sr. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Eliquis?

Eliquis has active ingredients of apixaban. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 191,859 Eliquis users. Check the latest studies of Eliquis.

What is Wellbutrin sr?

Wellbutrin sr has active ingredients of bupropion hydrochloride. It is often used in depression. eHealthMe is studying from 13,112 Wellbutrin sr users. Check the latest studies of Wellbutrin sr.

On Apr, 21, 2026

52 people who take Eliquis and Wellbutrin sr together, and have interactions are studied.

Eliquis and Wellbutrin sr drug interactions.

What are the common drug interactions of Eliquis and Wellbutrin Sr, by gender? *:

female:

Death
Fall
Fatigue (feeling of tiredness)
Headache (pain in head)
Postoperative wound infection
Atrial thrombosis (blood clot that develops in an artery)
Device related infection
Hospitalisation
Nasopharyngitis (inflammation of the nasopharynx)
Nausea (feeling of having an urge to vomit)

male:

Nausea (feeling of having an urge to vomit)
Urinary tract infection
Muscle spasms (muscle contraction)
Death
Herpes zoster
Adverse drug reaction
Back pain
Disease progression
Gout (uric acid crystals building up in the body)
Lactose intolerance (inability to digest lactose)

What are the common drug interactions of Eliquis and Wellbutrin Sr, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Atrial thrombosis (blood clot that develops in an artery)
Device related infection
Fatigue (feeling of tiredness)
Headache (pain in head)
Nasopharyngitis (inflammation of the nasopharynx)
Poor venous access
Postoperative wound infection
Suture rupture
Infusion site infection

30-39:

n/a

40-49:

n/a

50-59:

Feeling hot
Muscle spasms (muscle contraction)
Cardiac ventricular thrombosis (blood clot in ventricle)
Chills (felling of cold)
Dizziness
Fatigue (feeling of tiredness)
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Hypoaesthesia (reduced sense of touch or sensation)
Intracardiac thrombus (presence of a circumscribed mass with heart wall)
Nausea (feeling of having an urge to vomit)

60+:

Death
Nausea (feeling of having an urge to vomit)
Blood magnesium increased
Blood urea increased
Bone pain
Chronic kidney disease
Colon cancer
Cough
Diarrhoea
Dyspnoea exertional (breathlessness or shortness of breath)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 7 people, 13.46%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 5 people, 9.62%
Pain: 3 people, 5.77%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 5.77%
Idiopathic Pulmonary Fibrosis (chronic lung disease): 3 people, 5.77%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 3 people, 5.77%

* Approximation only. Some reports may have incomplete information.

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