Wellbutrin sr and Pradaxa drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Wellbutrin sr (bupropion hydrochloride) and Pradaxa (dabigatran etexilate mesylate). Common drug interactions include contusion among females and coagulopathy among males.
The phase IV clinical study analyzes what interactions people have when they take Wellbutrin sr and Pradaxa. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.
What is Wellbutrin sr?
Wellbutrin sr has active ingredients of bupropion hydrochloride. It is often used in depression. eHealthMe is studying from 13,112 Wellbutrin sr users. Check the latest studies of Wellbutrin sr.
What is Pradaxa?
Pradaxa has active ingredients of dabigatran etexilate mesylate. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 86,906 Pradaxa users. Check the latest studies of Pradaxa.
19 people who take Wellbutrin sr and Pradaxa together, and have interactions are studied.

What are the common drug interactions of Wellbutrin Sr and Pradaxa, by gender? *:
female:
- Contusion (a type of hematoma of tissue in which capillaries)
- Fall
- Heart rate increased
- Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
- Thermal burn (burn by heat)
- Abdominal pain
- Acute respiratory failure
- Faeces discoloured
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
male:
- Coagulopathy (blood's ability to clot is impaired)
- Epistaxis (bleed from the nose)
- Burning sensation
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Hypotension (abnormally low blood pressure)
- Pain
- Pulmonary embolism (blockage of the main artery of the lung)
- Pulseless electrical activity
- Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)
What are the common drug interactions of Wellbutrin Sr and Pradaxa, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Eyelid oedema (eyelids are swollen and contain excessive fluid)
- Oedema peripheral (superficial swelling)
- Skin irritation
- Swelling
- Swelling face
50-59:
- Acute respiratory failure
- Back pain
- Burning sensation
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Haematochezia (passage of stools containing blood)
- Interstitial lung disease
- Pain
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Spinal disorder (disease of spine a back bone)
- Therapeutic response decreased (less preventive response)
60+:
- Fall
- Coagulopathy (blood's ability to clot is impaired)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
- Disseminated intravascular coagulation (systemic activation of blood coagulation)
- Heart rate increased
- Hepatic failure (liver failure)
- Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
- Ischaemic hepatitis (decreased blood supply to the liver resulting in injury to liver cells)
- Lactic acidosis (low ph in body tissues)
What are the existing conditions these people have? *
- Pain: 6 people, 31.58%
- Itching: 3 people, 15.79%
- Dyspnea (difficult or laboured breathing): 3 people, 15.79%
- Neuralgia (pain in one or more nerves): 3 people, 15.79%
- Cardiac Disorder: 2 people, 10.53%
- Diabetes: 2 people, 10.53%
- High Blood Pressure: 2 people, 10.53%
- Irritable Bowel Syndrome: 1 person, 5.26%
- Cardiac Failure Congestive: 1 person, 5.26%
- Enlarged Prostate: 1 person, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Wellbutrin sr and Pradaxa?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Wellbutrin sr (13,112 reports)
- Pradaxa (86,906 reports)
Browse all drug interactions of Wellbutrin sr and Pradaxa:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Wellbutrin sr:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Pradaxa:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Wellbutrin sr and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pradaxa and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on bupropion hydrochloride and dabigatran etexilate mesylate (the active ingredients of Wellbutrin sr and Pradaxa, respectively), and Wellbutrin sr and Pradaxa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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