Wellbutrin and Eylea drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Wellbutrin (bupropion hydrochloride) and Eylea (aflibercept). Common drug interactions include eye irritation among females and blindness transient among males.

The phase IV clinical study analyzes what interactions people have when they take Wellbutrin and Eylea. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Wellbutrin?

Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. eHealthMe is studying from 117,107 Wellbutrin users. Check the latest studies of Wellbutrin.

What is Eylea?

Eylea has active ingredients of aflibercept. It is often used in macular degeneration. eHealthMe is studying from 27,868 Eylea users. Check the latest studies of Eylea.

On Jul, 12, 2026

22 people who take Wellbutrin and Eylea together, and have interactions are studied.

What are the common drug interactions of Wellbutrin and Eylea, by gender? *:

female:

Eye irritation
Eye pain
Inflammation
Uveitis (inflammation of the uvea)
Visual acuity reduced (reduced clearness of vision)
Visual impairment
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Decreased appetite
Dementia (madness)

male:

Blindness transient (sudden loss of vision)
Cataract (clouding of the lens inside the eye)
Dry eye (lack of adequate tears)
Eye inflammation
Headache (pain in head)
Iritis (painful inflammation of the iris of the eye)
Vision blurred
Vitreous detachment (a condition of the eye in which the vitreous humour separates from the retina)
Vitritis (inflammation of the vitreous humour of the eye)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

What are the common drug interactions of Wellbutrin and Eylea, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Decreased appetite
Weight decreased
Dementia (madness)
Drug ineffective
Eye disorder
Hunger
Libido decreased (loss of interest in sex)
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

Choroidal Neovascularisation (creation of new blood vessels in vascular layer of eye): 7 people, 31.82%
Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 4 people, 18.18%
Cyclitis (inflammation of the ciliary body (eye)): 3 people, 13.64%
Type 2 Diabetes: 2 people, 9.09%
Retinal Vessel Occlusion (a blockage in one of the small arteries): 2 people, 9.09%
Peripheral Arterial Occlusive Disease (reproducible ischemic muscle pain): 2 people, 9.09%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 2 people, 9.09%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 9.09%
High Blood Cholesterol: 2 people, 9.09%
Diabetic Retinopathy (damage to the retina caused by complications of diabetes): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Wellbutrin and Eylea?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously