Xarelto and Armodafinil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Xarelto (rivaroxaban) and Armodafinil (armodafinil). Common drug interactions include bronchitis among females and cystitis among males.

The phase IV clinical study analyzes what interactions people have when they take Xarelto and Armodafinil. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.

What is Xarelto?

Xarelto has active ingredients of rivaroxaban. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 212,377 Xarelto users. Check the latest studies of Xarelto.

What is Armodafinil?

Armodafinil has active ingredients of armodafinil. It is often used in narcolepsy. eHealthMe is studying from 4,136 Armodafinil users. Check the latest studies of Armodafinil.



On Jul, 18, 2026

54 people who take Xarelto and Armodafinil together, and have interactions are studied.

Xarelto and Armodafinil drug interactions.

What are the common drug interactions of Xarelto and Armodafinil, by gender? *:

female:

  1. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  2. Blood magnesium increased
  3. Chronic kidney disease
  4. Injection site reaction
  5. Oral infection
  6. Sinusitis (inflammation of sinus)
  7. Infusion site extravasation (flow of (blood or lymph) from infusion site)
  8. Asthma
  9. Head injury
  10. Headache (pain in head)

male:

  1. Cystitis (inflammation of the wall of the bladder)
  2. Oropharyngeal pain
  3. Unresponsive to stimuli
  4. Anxiety
  5. Intestinal resection
  6. Pain
  7. Post-traumatic stress disorder
  8. Lymphopenia (an abnormally low level of lymphocytes in the blood)
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Sexual dysfunction (difficulty experienced by an individual or a couple during any stage of a normal sexual activity)

What are the common drug interactions of Xarelto and Armodafinil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Accident
  2. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  3. Balance disorder
  4. Blindness unilateral
  5. Head injury
  6. Headache (pain in head)
  7. Hypoacusis (loss of hearing)
  8. Injury
  9. Neck injury
  10. Road traffic accident

40-49:

  1. Thrombosis (formation of a blood clot inside a blood vessel)
  2. Anxiety
  3. Depression
  4. Pulmonary embolism (blockage of the main artery of the lung)
  5. Migraine (headache)
  6. Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
  7. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  8. Overweight
  9. Shoulder operation
  10. Snoring

50-59:

  1. Asthma
  2. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  3. Infusion site extravasation (flow of (blood or lymph) from infusion site)
  4. Injection site reaction
  5. Oral infection
  6. Pneumonia
  7. Sinusitis (inflammation of sinus)
  8. Injection site extravasation (flow of (blood or lymph) from injection site)
  9. Injection site pruritus (severe itching at injection site)

60+:

  1. Hypertension (high blood pressure)
  2. Knee arthroplasty
  3. Sexual dysfunction (difficulty experienced by an individual or a couple during any stage of a normal sexual activity)
  4. Abdominal pain upper
  5. Anxiety
  6. Asthma
  7. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  8. Cardiac failure congestive
  9. Cystitis (inflammation of the wall of the bladder)
  10. Death

What are the existing conditions these people have? *

  1. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 15 people, 27.78%
  2. Drowsiness: 10 people, 18.52%
  3. Immunodeficiency Common Variable: 5 people, 9.26%
  4. Stress And Anxiety: 3 people, 5.56%
  5. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 5.56%
  6. Prostatic Disorder: 3 people, 5.56%
  7. Kidney Stones: 3 people, 5.56%
  8. High Blood Pressure: 3 people, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Xarelto and Armodafinil?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Xarelto and Armodafinil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Xarelto:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Armodafinil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Xarelto and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Armodafinil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on rivaroxaban and armodafinil (the active ingredients of Xarelto and Armodafinil, respectively), and Xarelto and Armodafinil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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