Xarelto and Ingrezza drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Xarelto (rivaroxaban) and Ingrezza (valbenazine tosylate). Common drug interactions include fall among females and somnolence among males.

The phase IV clinical study analyzes what interactions people have when they take Xarelto and Ingrezza. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Xarelto?

Xarelto has active ingredients of rivaroxaban. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 212,377 Xarelto users. Check the latest studies of Xarelto.

What is Ingrezza?

Ingrezza has active ingredients of valbenazine tosylate. eHealthMe is studying from 23,666 Ingrezza users. Check the latest studies of Ingrezza.



On Jul, 23, 2026

50 people who take Xarelto and Ingrezza together, and have interactions are studied.

Xarelto and Ingrezza drug interactions.

What are the common drug interactions of Xarelto and Ingrezza, by gender? *:

female:

  1. Fall
  2. Somnolence (a state of near-sleep, a strong desire for sleep)
  3. Arthralgia (joint pain)
  4. Pruritus generalised (generalized itching)
  5. Dry mouth
  6. Gingival erosion (gum ulcer)
  7. Urinary tract infection
  8. Dizziness
  9. Memory impairment
  10. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)

male:

  1. Somnolence (a state of near-sleep, a strong desire for sleep)
  2. Back pain
  3. Anxiety
  4. Blood pressure decreased
  5. Fatigue (feeling of tiredness)
  6. Hospitalisation
  7. Insomnia (sleeplessness)
  8. Rehabilitation therapy
  9. Cardiac arrest
  10. Coronary artery bypass

What are the common drug interactions of Xarelto and Ingrezza, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Headache (pain in head)
  2. Neck pain

50-59:

  1. Fall
  2. Memory impairment
  3. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  4. Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)
  5. Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
  6. Adverse drug reaction
  7. Balance disorder
  8. Dizziness
  9. Dyskinesia (abnormality or impairment of voluntary movement)
  10. Nausea (feeling of having an urge to vomit)

60+:

  1. Somnolence (a state of near-sleep, a strong desire for sleep)
  2. Fall
  3. Cough
  4. Disturbance in attention
  5. Dizziness
  6. Dyspnoea (difficult or laboured respiration)
  7. Feeling jittery
  8. Ligament sprain (ligament stretched)
  9. Neck pain
  10. Oedema (fluid collection in tissue)

What are the existing conditions these people have? *

  1. Tardive Dyskinesia (a disorder that involves involuntary movements): 37 people, 74.00%
  2. Stress And Anxiety: 8 people, 16.00%
  3. Thrombosis (formation of a blood clot inside a blood vessel): 4 people, 8.00%
  4. Sleep Disorder: 3 people, 6.00%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.00%
  6. Depression: 3 people, 6.00%
  7. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 3 people, 6.00%

* Approximation only. Some reports may have incomplete information.

Do you take Xarelto and Ingrezza?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Xarelto and Ingrezza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Xarelto:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ingrezza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Xarelto and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ingrezza and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on rivaroxaban and valbenazine tosylate (the active ingredients of Xarelto and Ingrezza, respectively), and Xarelto and Ingrezza (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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