Xcopri and Diacomit drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Xcopri (cenobamate) and Diacomit (stiripentol). Common drug interactions include seizure among females and anger among males.

The phase IV clinical study analyzes what interactions people have when they take Xcopri and Diacomit. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Xcopri?

Xcopri has active ingredients of cenobamate. eHealthMe is studying from 4,142 Xcopri users. Check the latest studies of Xcopri.

What is Diacomit?

Diacomit has active ingredients of stiripentol. eHealthMe is studying from 1,686 Diacomit users. Check the latest studies of Diacomit.

On Jul, 15, 2026

26 people who take Xcopri and Diacomit together, and have interactions are studied.

What are the common drug interactions of Xcopri and Diacomit, by gender? *:

female:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Dyspnoea (difficult or laboured respiration)
Somnolence (a state of near-sleep, a strong desire for sleep)
Abdominal pain upper
Death
Dehydration (dryness resulting from the removal of water)
Drug ineffective
Ear infection
Alopecia (absence of hair from areas of the body)
Appetite disorder (abnormal eating habits)

male:

Anger
Dizziness
Vomiting
Fatigue (feeling of tiredness)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Adverse event
Aggression
Drooling (drop saliva uncontrollably from the mouth)
Insomnia (sleeplessness)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)

What are the common drug interactions of Xcopri and Diacomit, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Abdominal pain upper
Dehydration (dryness resulting from the removal of water)
Drug ineffective
Ear infection
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

10-19:

Anger
Dizziness
Fatigue (feeling of tiredness)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Aggression
Drooling (drop saliva uncontrollably from the mouth)
Insomnia (sleeplessness)
Stomatitis (inflammation of mucous membrane of mouth)
Vomiting

20-29:

Dyspnoea (difficult or laboured respiration)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Somnolence (a state of near-sleep, a strong desire for sleep)
Death

30-39:

n/a

40-49:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Lennox-Gastaut Syndrome (epilepsy characterized by frequent seizures and different seizure types): 5 people, 19.23%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 4 people, 15.38%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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