Xolair and Oxycontin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Xolair (omalizumab) and Oxycontin (oxycodone hydrochloride). Common drug interactions include impaired gastric emptying among females and drug withdrawal syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Xolair and Oxycontin. It is created by eHealthMe based on reports of 76 people who take the same drugs from the FDA, and is updated regularly.

What is Xolair?

Xolair has active ingredients of omalizumab. It is often used in asthma. eHealthMe is studying from 77,555 Xolair users. Check the latest studies of Xolair.

What is Oxycontin?

Oxycontin has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 212,533 Oxycontin users. Check the latest studies of Oxycontin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

76 people who take Xolair and Oxycontin together, and have interactions are studied.

What are the common drug interactions of Xolair and Oxycontin, by gender? *:

female:

Impaired gastric emptying
Loss of consciousness
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pain in extremity
Palpitations (feelings or sensations that your heart is pounding or racing)
Renal failure acute (rapid kidney dysfunction)
Secretion discharge
Swelling face
Wheezing (a high-pitched whistling sound made while you breath)
Aphasia (damage to the parts of the brain that control language)

male:

Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
C-reactive protein increased
Dyspnoea (difficult or laboured respiration)
Forced expiratory volume decreased (decreased lung expired air volume)
General physical health deterioration (weak health status)
Headache (pain in head)
Hypertension (high blood pressure)
Inflammation
Injected limb mobility decreased

What are the common drug interactions of Xolair and Oxycontin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Respiratory tract inflammation
Blood alkaline phosphatase increased
C-reactive protein increased
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Forced expiratory volume decreased (decreased lung expired air volume)
General physical health deterioration (weak health status)
Headache (pain in head)
Hypertension (high blood pressure)
Inflammation

40-49:

Blood pressure increased
Headache (pain in head)
Injection site erythema (redness at injection site)
Lower respiratory tract infection
Lymphadenopathy (disease or enlargement of lymph nodes)
Nausea (feeling of having an urge to vomit)
Cough
Sputum discoloured
Pneumonia
Asthenia (weakness)

50-59:

Aphasia (damage to the parts of the brain that control language)
Breakthrough pain
Cardiac disorder
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chest pain
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Decreased appetite
Depression
Dysarthria (speech disorder)
Ejection fraction (the percentage of blood that is pumped out of a filled ventricle as a result of a heartbeat)

60+:

Blood pressure increased
Pyrexia (fever)
Myalgia (muscle pain)
Nasopharyngitis (inflammation of the nasopharynx)
Red cell distribution width increased
Seasonal allergy (allergic condition due to certain season)
Stress
Vomiting
Weight decreased
Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 7.89%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 5.26%
Anaemia (lack of blood): 4 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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