Xopenex and Actemra drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Xopenex (levalbuterol hydrochloride) and Actemra (tocilizumab). Common drug interactions include drug ineffective among females and asthenia among males.
The phase IV clinical study analyzes what interactions people have when they take Xopenex and Actemra. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.
What is Xopenex?
Xopenex has active ingredients of levalbuterol hydrochloride. It is often used in asthma. eHealthMe is studying from 13,816 Xopenex users. Check the latest studies of Xopenex.
What is Actemra?
Actemra has active ingredients of tocilizumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 102,759 Actemra users. Check the latest studies of Actemra.
33 people who take Xopenex and Actemra together, and have interactions are studied.

What are the common drug interactions of Xopenex and Actemra, by gender? *:
female:
- Drug ineffective
- Fluid retention (an abnormal accumulation of fluid in the blood)
- Muscle spasms (muscle contraction)
- Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
- Depression
- Drug hypersensitivity
- Gastric disorder (disease of stomach)
- Sinusitis (inflammation of sinus)
- Surgery
- Abdominal pain
male:
- Asthenia (weakness)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Decreased appetite
- Diarrhoea
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Ear infection
- Fatigue (feeling of tiredness)
- Headache (pain in head)
- Nausea (feeling of having an urge to vomit)
- Weight decreased
What are the common drug interactions of Xopenex and Actemra, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Anaphylactic reaction (serious allergic reaction)
- Behcet's syndrome (involves inflammation of the blood vessels)
- Blood pressure increased
- Dyspnoea (difficult or laboured respiration)
- Fracture
- Heart rate increased
- Hyperventilation
- Hypoaesthesia (reduced sense of touch or sensation)
- Pain
- Panic attack
40-49:
- Pneumonitis (inflammation of the walls of the alveoli in the lungs)
- Anaphylactic reaction (serious allergic reaction)
- Dyspnoea (difficult or laboured respiration)
- Pulmonary mass
50-59:
- Gastric disorder (disease of stomach)
- Muscle spasms (muscle contraction)
- Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
- Surgery
- Asthenia (weakness)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Decreased appetite
- Diarrhoea
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Ear infection
60+:
- Abdominal pain
- Flushing (the warm, red condition of human skin)
- Drug ineffective
- Drug resistance (reduction in effectiveness of a drug)
- Dyspnoea (difficult or laboured respiration)
- Hypersensitivity
- Thrombocytopenia (decrease of platelets in blood)
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 13 people, 39.39%
- Immunodeficiency Common Variable: 6 people, 18.18%
- Immunodeficiency: 5 people, 15.15%
- Pain: 4 people, 12.12%
- Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 4 people, 12.12%
- Hypersensitivity: 3 people, 9.09%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 9.09%
- Stress And Anxiety: 2 people, 6.06%
- Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 2 people, 6.06%
- High Blood Pressure: 2 people, 6.06%
* Approximation only. Some reports may have incomplete information.
Do you take Xopenex and Actemra?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Xopenex and Actemra:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Xopenex:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Actemra:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Xopenex and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Actemra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on levalbuterol hydrochloride and tocilizumab (the active ingredients of Xopenex and Actemra, respectively), and Xopenex and Actemra (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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