Xopenex and Naloxone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Xopenex (levalbuterol hydrochloride) and Naloxone (naloxone hydrochloride). Common drug interactions include hypokinesia among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Xopenex and Naloxone. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Xopenex?

Xopenex has active ingredients of levalbuterol hydrochloride. It is often used in asthma. eHealthMe is studying from 13,816 Xopenex users. Check the latest studies of Xopenex.

What is Naloxone?

Naloxone has active ingredients of naloxone hydrochloride. eHealthMe is studying from 6,425 Naloxone users. Check the latest studies of Naloxone.



On Jul, 06, 2026

24 people who take Xopenex and Naloxone together, and have interactions are studied.

Xopenex and Naloxone drug interactions.

What are the common drug interactions of Xopenex and Naloxone, by gender? *:

female:

  1. Hypokinesia (decreased bodily movement)
  2. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  3. Impaired work ability
  4. Pain
  5. Ascites (accumulation of fluid in the abdominal cavity)
  6. Fibromyalgia (a long-term condition which causes pain all over the body)
  7. Metastases to liver (cancer spreads to liver)
  8. Metastases to peritoneum (cancer spreads to peritoneum)
  9. Ovarian cancer metastatic (cancer of ovary spreads to other organ or parts)
  10. Pancreatic carcinoma metastatic (pancreatic cancer- metastatic)

male:

  1. Arthralgia (joint pain)
  2. Back pain
  3. Productive cough
  4. Sepsis (a severe blood infection that can lead to organ failure and death)
  5. Dyspnoea exertional (breathlessness or shortness of breath)
  6. Gastric disorder (disease of stomach)
  7. Head injury
  8. Malignant neoplasm progression (cancer tumour came back)
  9. Sleep disorder
  10. Chronic kidney disease

What are the common drug interactions of Xopenex and Naloxone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Malignant neoplasm progression (cancer tumour came back)
  2. Sepsis (a severe blood infection that can lead to organ failure and death)

20-29:

n/a

30-39:

n/a

40-49:

  1. Fibromyalgia (a long-term condition which causes pain all over the body)
  2. Hypokinesia (decreased bodily movement)
  3. Pain
  4. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  5. Impaired work ability

50-59:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)

60+:

  1. Ascites (accumulation of fluid in the abdominal cavity)
  2. Metastases to liver (cancer spreads to liver)
  3. Generalised oedema (swelling all over the body)
  4. Headache (pain in head)
  5. Hepatic steatosis (fatty liver disease)
  6. Hypervolaemia (abnormally increased volume of blood)
  7. Metastases to lymph nodes (cancer spreads to lymph node)
  8. Metastatic lymphoma (spreadable cancer tumour of lymph node)
  9. Pancreatitis (inflammation of pancreas)
  10. Pancreatitis acute (sudden inflammation of pancreas)

What are the existing conditions these people have? *

  1. Stress And Anxiety: 8 people, 33.33%
  2. Wheezing (a high-pitched whistling sound made while you breath): 7 people, 29.17%
  3. Muscle Aches (muscle pain): 7 people, 29.17%
  4. Fibromyalgia (a long-term condition which causes pain all over the body): 7 people, 29.17%
  5. Primary Immunodeficiency Syndrome: 6 people, 25.00%
  6. Immunodeficiency Common Variable: 6 people, 25.00%
  7. Pain: 2 people, 8.33%
  8. Nausea (feeling of having an urge to vomit): 2 people, 8.33%
  9. Multiple Allergies (allergy to multiple agents): 2 people, 8.33%
  10. Insomnia (sleeplessness): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Xopenex and Naloxone?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Xopenex and Naloxone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Xopenex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Naloxone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Xopenex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Naloxone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on levalbuterol hydrochloride and naloxone hydrochloride (the active ingredients of Xopenex and Naloxone, respectively), and Xopenex and Naloxone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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