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Xtandi and Ms contin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Xtandi (enzalutamide) and Ms contin (morphine sulfate). Common drug interactions include malignant neoplasm progression among males.

The phase IV clinical study analyzes what interactions people have when they take Xtandi and Ms contin. It is created by eHealthMe based on reports of 99 people who take the same drugs from the FDA, and is updated regularly.

What is Xtandi?

Xtandi has active ingredients of enzalutamide. eHealthMe is studying from 51,498 Xtandi users. Check the latest studies of Xtandi.

What is Ms contin?

Ms contin has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 69,289 Ms contin users. Check the latest studies of Ms contin.

On Jul, 10, 2026

99 people who take Xtandi and Ms contin together, and have interactions are studied.

Xtandi and Ms contin drug interactions.

What are the common drug interactions of Xtandi and Ms Contin, by gender? *:

female:

n/a

male:

  1. Malignant neoplasm progression (cancer tumour came back)
  2. Prostatic specific antigen increased
  3. Hot flush (sudden feelings of heat)
  4. Headache (pain in head)
  5. Asthenia (weakness)
  6. Diarrhoea
  7. Fall
  8. Anaemia (lack of blood)
  9. Breast tenderness
  10. Hypersensitivity

What are the common drug interactions of Xtandi and Ms Contin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Anaemia (lack of blood)
  2. Asthenia (weakness)
  3. Death
  4. Decreased appetite
  5. Diarrhoea haemorrhagic (bloody diarrhoea)
  6. Dyspnoea (difficult or laboured respiration)
  7. Heart rate increased
  8. Hypotension (abnormally low blood pressure)
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Nausea (feeling of having an urge to vomit)

50-59:

  1. Thrombocytopenia (decrease of platelets in blood)
  2. Asthenia (weakness)
  3. Confusional state
  4. Constipation
  5. Dysstasia (difficulty in standing)
  6. Neoplasm (tumour)
  7. Ulcer haemorrhage (bleeding ulcer)
  8. Abdominal distension
  9. Cough
  10. Decreased appetite

60+:

  1. Malignant neoplasm progression (cancer tumour came back)
  2. Prostatic specific antigen increased
  3. Hypersensitivity
  4. Increased bronchial secretion
  5. Increased upper airway secretion
  6. Cough
  7. Death
  8. Confusional state
  9. Fall
  10. Flushing (the warm, red condition of human skin)

What are the existing conditions these people have? *

  1. Prostate Cancer: 72 people, 72.73%
  2. Prostate Cancer Metastatic: 13 people, 13.13%
  3. Nausea (feeling of having an urge to vomit): 7 people, 7.07%

* Approximation only. Some reports may have incomplete information.

Do you take Xtandi and Ms contin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Xtandi and Ms contin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Xtandi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ms contin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Xtandi and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ms contin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on enzalutamide and morphine sulfate (the active ingredients of Xtandi and Ms contin, respectively), and Xtandi and Ms contin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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