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Xyzal and Tolterodine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Xyzal (levocetirizine dihydrochloride) and Tolterodine (tolterodine tartrate). Common drug interactions include allergy to plants among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Xyzal and Tolterodine. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Xyzal?

Xyzal has active ingredients of levocetirizine dihydrochloride. It is often used in allergies. eHealthMe is studying from 21,479 Xyzal users. Check the latest studies of Xyzal.

What is Tolterodine?

Tolterodine has active ingredients of tolterodine tartrate. It is often used in urge incontinence. eHealthMe is studying from 8,156 Tolterodine users. Check the latest studies of Tolterodine.

On Jul, 17, 2026

11 people who take Xyzal and Tolterodine together, and have interactions are studied.

Xyzal and Tolterodine drug interactions.

What are the common drug interactions of Xyzal and Tolterodine, by gender? *:

female:

  1. Allergy to plants
  2. Blood pressure increased
  3. Body temperature decreased
  4. Constipation
  5. Cough
  6. Diarrhoea
  7. Dyspnoea (difficult or laboured respiration)
  8. Ear pain
  9. Fall
  10. Fatigue (feeling of tiredness)

male:

  1. Asthenia (weakness)
  2. Cardiac arrest
  3. Haemoglobin decreased
  4. Hallucination (an experience involving the perception of something not present)
  5. Hospitalisation
  6. Nausea (feeling of having an urge to vomit)
  7. Pulmonary oedema (fluid accumulation in the lungs)
  8. Urinary tract infection
  9. Vomiting
  10. Chronic kidney disease

What are the common drug interactions of Xyzal and Tolterodine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Chronic kidney disease

60+:

  1. Diarrhoea
  2. Allergy to plants
  3. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  4. Hypersensitivity
  5. Infection
  6. Influenza
  7. Influenza like illness
  8. Infusion related reaction
  9. Insomnia (sleeplessness)
  10. Intestinal obstruction

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 4 people, 36.36%
  2. Prostate Cancer: 2 people, 18.18%
  3. Diabetes: 2 people, 18.18%
  4. Tardive Dyskinesia (a disorder that involves involuntary movements): 1 person, 9.09%
  5. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 1 person, 9.09%
  6. Back Pain: 1 person, 9.09%
  7. Bladder Disorder: 1 person, 9.09%
  8. Depression: 1 person, 9.09%
  9. Eye Disorder: 1 person, 9.09%
  10. Hypersensitivity: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Xyzal and Tolterodine?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Xyzal and Tolterodine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Xyzal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tolterodine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Xyzal and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tolterodine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on levocetirizine dihydrochloride and tolterodine tartrate (the active ingredients of Xyzal and Tolterodine, respectively), and Xyzal and Tolterodine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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