Yasmin and Prograf drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Yasmin (drospirenone; ethinyl estradiol) and Prograf (tacrolimus). Common drug interactions include hypertension among females and local swelling among males.

The phase IV clinical study analyzes what interactions people have when they take Yasmin and Prograf. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Yasmin?

Yasmin has active ingredients of drospirenone; ethinyl estradiol. It is often used in birth control. eHealthMe is studying from 48,855 Yasmin users. Check the latest studies of Yasmin.

What is Prograf?

Prograf has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 42,230 Prograf users. Check the latest studies of Prograf.

On Jul, 12, 2026

35 people who take Yasmin and Prograf together, and have interactions are studied.

What are the common drug interactions of Yasmin and Prograf, by gender? *:

female:

Hypertension (high blood pressure)
Dizziness
Drug ineffective
Dyspepsia (indigestion)
Ear discomfort
Erythema (redness of the skin)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cholecystitis chronic (long lasting infection of gallbladder)
Nausea (feeling of having an urge to vomit)
Injury

male:

Local swelling (swelling at the site of some application of substance or injury)
Pulmonary embolism (blockage of the main artery of the lung)
Renal cell carcinoma (a kidney cancer)
Cholecystitis (infection of gallbladder)
Cholecystitis chronic (long lasting infection of gallbladder)
Constipation
Diarrhoea
Transplant rejection (a transplant material is not worked)

What are the common drug interactions of Yasmin and Prograf, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal distension
Abdominal pain
Anxiety
Attention deficit/hyperactivity disorder
Balance disorder
Biliary colic
Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Cold sweat
Constipation

20-29:

Haemolytic uraemic syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more)
Hypertension (high blood pressure)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Hypotension (abnormally low blood pressure)
Impaired driving ability
Leukocytosis (increased white blood cells)
Lymphocyte count decreased
Nephrolithiasis (calculi in the kidneys)
Neuropathy peripheral (surface nerve damage)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)

30-39:

Pain
Injury
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Glomerular filtration rate decreased
Headache (pain in head)
Hypertension (high blood pressure)
Nausea (feeling of having an urge to vomit)
Normochromic normocytic anaemia (forms of anaemia in which the average size and haemoglobin content of the red blood cells are within normal limits)
Palpitations (feelings or sensations that your heart is pounding or racing)

40-49:

Dyspnoea (difficult or laboured respiration)
Chest pain
Heart injury
Heart rate irregular
Pain
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Local swelling (swelling at the site of some application of substance or injury)
Pulmonary embolism (blockage of the main artery of the lung)
Renal cell carcinoma (a kidney cancer)
Anaemia of chronic disease

50-59:

n/a

60+:

Cholecystitis chronic (long lasting infection of gallbladder)
Diarrhoea
Emotional distress
Nausea (feeling of having an urge to vomit)
Pain
Transplant rejection (a transplant material is not worked)
Vomiting
Cholecystitis (infection of gallbladder)
Cholecystitis infective (infection of gallbladder capable to infect other organs)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 22.86%
Pain: 7 people, 20.00%
Depression: 7 people, 20.00%
Headache (pain in head): 5 people, 14.29%
Stress And Anxiety: 5 people, 14.29%
Acne (skin problems that cause pimples): 5 people, 14.29%
Thyroid Diseases: 4 people, 11.43%
Parathyroid Disorder: 3 people, 8.57%
Immune System Disorder: 3 people, 8.57%
Premenstrual Syndrome: 3 people, 8.57%

* Approximation only. Some reports may have incomplete information.

Do you take Yasmin and Prograf?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously