Yasmin and Soliris drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Yasmin (drospirenone; ethinyl estradiol) and Soliris (eculizumab). Common drug interactions include haemoglobin decreased among females and benign pancreatic neoplasm among males.

The phase IV clinical study analyzes what interactions people have when they take Yasmin and Soliris. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Yasmin?

Yasmin has active ingredients of drospirenone; ethinyl estradiol. It is often used in birth control. eHealthMe is studying from 48,855 Yasmin users. Check the latest studies of Yasmin.

What is Soliris?

Soliris has active ingredients of eculizumab. It is often used in paroxysmal nocturnal hemoglobinuria (pnh). eHealthMe is studying from 58,821 Soliris users. Check the latest studies of Soliris.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

15 people who take Yasmin and Soliris together, and have interactions are studied.

What are the common drug interactions of Yasmin and Soliris, by gender? *:

female:

Haemoglobin decreased
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Muscle spasms (muscle contraction)
Pain
Alcohol intolerance
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Hot flush (sudden feelings of heat)
Hyperhidrosis (abnormally increased sweating)
Weight increased
Blood lactate dehydrogenase increased

male:

Benign pancreatic neoplasm (benign (non-cancerous) tumours of the pancreatic)
Cholecystitis (infection of gallbladder)
Gallbladder disorder
Hepatic cyst
Injury
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Pain
Pneumobilia (presence of gas in the biliary system)

What are the common drug interactions of Yasmin and Soliris, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Renal failure (kidney dysfunction)
Serum ferritin increased
Swelling face
Thrombocytopenia (decrease of platelets in blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Blood creatinine increased
Blood potassium increased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cholecystitis (infection of gallbladder)

30-39:

Pain
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Joint swelling
Meningococcal sepsis (meningococcal infection to whole body)
Abdominal pain
Blood uric acid increased
Diarrhoea haemorrhagic (bloody diarrhoea)
Emotional distress
Helminthic infection (worms infection)
Injury

40-49:

Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Back pain
Chest pain
Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Drug ineffective
Dysphagia (a condition in which swallowing is difficult or painful)
Emotional distress
Epistaxis (bleed from the nose)
Fatigue (feeling of tiredness)

50-59:

n/a

60+:

Benign pancreatic neoplasm (benign (non-cancerous) tumours of the pancreatic)
Cholecystitis (infection of gallbladder)
Gallbladder disorder
Hepatic cyst
Injury
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Pain
Pneumobilia (presence of gas in the biliary system)

What are the existing conditions these people have? *

Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 13 people, 86.67%
Depression: 3 people, 20.00%
Indigestion: 2 people, 13.33%
Pain: 2 people, 13.33%
Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 2 people, 13.33%
Premenstrual Syndrome: 2 people, 13.33%
Herpes Virus Infection: 1 person, 6.67%
Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain): 1 person, 6.67%
Glucose Tolerance Impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis): 1 person, 6.67%
Headache (pain in head): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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