Zaleplon and Benicar drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Zaleplon (zaleplon) and Benicar (olmesartan medoxomil). Common drug interactions include fall among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Zaleplon and Benicar. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.
What is Zaleplon?
Zaleplon has active ingredients of zaleplon. It is often used in insomnia. eHealthMe is studying from 1,935 Zaleplon users. Check the latest studies of Zaleplon.
What is Benicar?
Benicar has active ingredients of olmesartan medoxomil. It is often used in high blood pressure. eHealthMe is studying from 36,002 Benicar users. Check the latest studies of Benicar.
21 people who take Zaleplon and Benicar together, and have interactions are studied.

What are the common drug interactions of Zaleplon and Benicar, by gender? *:
female:
- Fall
- Fungal infection
- Hand fracture
- Localised infection (infection at the single location)
- Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
- Pneumonia
- Seasonal allergy (allergic condition due to certain season)
- Tooth abscess (pus formation in tooth)
- Tooth fracture
- Upper respiratory tract infection
male:
- Chronic kidney disease
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
What are the common drug interactions of Zaleplon and Benicar, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Anaemia (lack of blood)
- Chronic kidney disease
- Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
- Gastritis (inflammation of stomach)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Haemorrhoids (a swollen vein or group of veins in the region of the anus)
- Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract)
- Nephrogenic anaemia (anaemia due to kidney disease)
60+:
- Cystitis (inflammation of the wall of the bladder)
- Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
- Sinusitis (inflammation of sinus)
- Urinary tract infection
- Chronic kidney disease
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
- Tooth abscess (pus formation in tooth)
- Tooth fracture
- Upper respiratory tract infection
What are the existing conditions these people have? *
- Immunodeficiency Common Variable: 8 people, 38.10%
- Urinary Tract Infection: 6 people, 28.57%
- Pain: 4 people, 19.05%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 19.05%
- Infection: 3 people, 14.29%
- High Blood Cholesterol: 3 people, 14.29%
- Oedema (fluid collection in tissue): 2 people, 9.52%
- Nausea And Vomiting: 2 people, 9.52%
- Nausea (feeling of having an urge to vomit): 2 people, 9.52%
- Multiple Allergies (allergy to multiple agents): 2 people, 9.52%
* Approximation only. Some reports may have incomplete information.
Do you take Zaleplon and Benicar?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Zaleplon and Benicar:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Zaleplon:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Benicar:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zaleplon and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Benicar and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on zaleplon and olmesartan medoxomil (the active ingredients of Zaleplon and Benicar, respectively), and Zaleplon and Benicar (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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