Zaleplon and Vesicare drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zaleplon (zaleplon) and Vesicare (solifenacin succinate). Common drug interactions include pain among females and cholecystitis chronic among males.

The phase IV clinical study analyzes what interactions people have when they take Zaleplon and Vesicare. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Zaleplon?

Zaleplon has active ingredients of zaleplon. It is often used in insomnia. eHealthMe is studying from 1,935 Zaleplon users. Check the latest studies of Zaleplon.

What is Vesicare?

Vesicare has active ingredients of solifenacin succinate. It is often used in urge incontinence. eHealthMe is studying from 30,655 Vesicare users. Check the latest studies of Vesicare.

On Aug, 02, 2026

28 people who take Zaleplon and Vesicare together, and have interactions are studied.

Zaleplon and Vesicare drug interactions.

What are the common drug interactions of Zaleplon and Vesicare, by gender? *:

female:

Pain
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Gallbladder disorder
Vision blurred
Anxiety
Breast cancer
Cholecystitis chronic (long lasting infection of gallbladder)
Depression
Dizziness
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

male:

Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Nephrogenic anaemia (anaemia due to kidney disease)
Pruritus generalised (generalized itching)
Renal failure (kidney dysfunction)
Gallbladder disorder
Pain
Chronic kidney disease
Coronary arterial stent insertion
Death

What are the common drug interactions of Zaleplon and Vesicare, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Gallbladder disorder
Pain
Cholecystitis chronic (long lasting infection of gallbladder)

40-49:

Breast cancer
Nausea (feeling of having an urge to vomit)
Arthralgia (joint pain)
Blood cholesterol increased
Blood triglycerides increased
Candidiasis (candidiasis or thrush is a fungal infection)
Constipation
Dysgeusia (disorder of the sense of taste)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hyperlipidaemia (presence of excess lipids in the blood)

50-59:

Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Dizziness
Gallbladder disorder
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Pain
Vision blurred
Blindness transient (sudden loss of vision)
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Death

60+:

Anxiety
Depression
Nephrogenic anaemia (anaemia due to kidney disease)
Oesophageal obstruction (blockage of oesophagus)
Pneumonia
Pruritus generalised (generalized itching)
Renal failure (kidney dysfunction)
Surgery
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Viral infection

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 28.57%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 17.86%
Sleep Disorder: 4 people, 14.29%
Premenstrual Syndrome: 4 people, 14.29%
Birth Control: 4 people, 14.29%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 10.71%
Stress And Anxiety: 2 people, 7.14%
Restless Leg Syndrome (a powerful urge to move your legs): 2 people, 7.14%
Osteopenia (a condition where bone mineral density is lower than normal): 2 people, 7.14%
Migraine (headache): 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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