Zantac and Elspar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zantac (ranitidine hydrochloride) and Elspar (asparaginase). Common drug interactions include convulsions among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Zantac and Elspar. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Zantac?

Zantac has active ingredients of ranitidine hydrochloride. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 434,161 Zantac users. Check the latest studies of Zantac.

What is Elspar?

Elspar has active ingredients of asparaginase. eHealthMe is studying from 2,057 Elspar users. Check the latest studies of Elspar.

On Jul, 09, 2026

12 people who take Zantac and Elspar together, and have interactions are studied.

What are the common drug interactions of Zantac and Elspar, by gender? *:

female:

Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Abdominal distension
Abdominal pain
Abdominal pain lower
Acute abdomen
Anaemia (lack of blood)
Blood culture positive
Blood pressure decreased
Cardiac disorder

male:

Abdominal pain
Abscess bacterial (collection of pus caused by bacteria)
Cardiomegaly (increased size of heart than normal)
Catheter related infection
Clostridium colitis (inflammation of colon by clostridium difficile bacteria infection)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Dyspnoea (difficult or laboured respiration)
Enterococcal infection
Febrile neutropenia (fever with reduced white blood cells)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)

What are the common drug interactions of Zantac and Elspar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Abdominal distension
Abdominal pain
Anaemia (lack of blood)
Blood pressure decreased
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Decreased activity
Eye movement disorder
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Hypovolaemia (a decreased volume of circulating blood in the body)
Infarction (obstruction of the blood supply to an organ or region of tissue)

10-19:

Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Hemiparesis (weakness on one side of the body)
Superior sagittal sinus thrombosis (blood clot in the dural venous sinuses, which drain blood from the brain)

20-29:

n/a

30-39:

Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
Parkinsonism (degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination)

40-49:

n/a

50-59:

n/a

60+:

Abdominal pain lower
Acute abdomen
Faecal occult blood (blood clot in stool)
Gastrointestinal perforation (hole in the digestive tract)
Hyperammonaemia
Intestinal obstruction
Pancreatitis (inflammation of pancreas)
Pneumonia
Pyrexia (fever)
Sepsis (a severe blood infection that can lead to organ failure and death)

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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