Zantac and Flurbiprofen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zantac (ranitidine hydrochloride) and Flurbiprofen (flurbiprofen). Common drug interactions include chest discomfort among females and acute myeloid leukaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Zantac and Flurbiprofen. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Zantac?

Zantac has active ingredients of ranitidine hydrochloride. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 434,161 Zantac users. Check the latest studies of Zantac.

What is Flurbiprofen?

Flurbiprofen has active ingredients of flurbiprofen. It is often used in rheumatoid arthritis. eHealthMe is studying from 2,677 Flurbiprofen users. Check the latest studies of Flurbiprofen.

On Jul, 15, 2026

28 people who take Zantac and Flurbiprofen together, and have interactions are studied.

Zantac and Flurbiprofen drug interactions.

What are the common drug interactions of Zantac and Flurbiprofen, by gender? *:

female:

Chest discomfort
Chest pain
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Dyslipidaemia (abnormal amount of lipids)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Faeces discoloured
Femur fracture
Fracture nonunion (permanent failure of healing following a broken bone)

male:

Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Pneumonia
Candidiasis (candidiasis or thrush is a fungal infection)
Cerebral haemorrhage (bleeding within the brain)
Death
Dehydration (dryness resulting from the removal of water)
Depressed level of consciousness
Disseminated tuberculosis
Endocarditis bacterial (an inflammation of the inner layer of the heart by bacterial infection)
Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)

What are the common drug interactions of Zantac and Flurbiprofen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
Subcutaneous abscess
Vomiting
White blood cell count decreased
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Upper respiratory tract inflammation
Acidosis (build-up of carbon dioxide in the blood)
Alanine aminotransferase increased
Alpha haemolytic streptococcal infection (infections with alpha-haemolytic strep bacteria are common; many strains live naturally in humans)
Aspartate aminotransferase increased

40-49:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pulmonary embolism (blockage of the main artery of the lung)

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Chest discomfort
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Palpitations (feelings or sensations that your heart is pounding or racing)
Renal injury (kidney injury)

60+:

Chronic gastritis (long lasting infection of stomach lining)
Diarrhoea
Abdominal pain
Abdominal pain upper
Anal fissure
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Bacterial infection
Blood pressure diastolic increased
Bone marrow depression (decreased ability or inability of the bone marrow to produce blood cells)
Cardiac failure

What are the existing conditions these people have? *

Visual Impairment: 3 people, 10.71%
Pain: 3 people, 10.71%
Osteoporosis (bones weak and more likely to break): 3 people, 10.71%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 10.71%
Inflammation: 3 people, 10.71%
Eye Infection: 3 people, 10.71%
Diabetes: 3 people, 10.71%
Carpal Tunnel Syndrome (nerve compression at wrist results numbness weakness, pain , swelling): 3 people, 10.71%
Allergic Rhinitis: 3 people, 10.71%
Jaundice - Yellow Skin (a yellowish pigmentation of the skin): 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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