Zantac and Tarka drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zantac (ranitidine hydrochloride) and Tarka (trandolapril; verapamil hydrochloride). Common drug interactions include deep vein thrombosis among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Zantac and Tarka. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Zantac?

Zantac has active ingredients of ranitidine hydrochloride. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 434,161 Zantac users. Check the latest studies of Zantac.

What is Tarka?

Tarka has active ingredients of trandolapril; verapamil hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 2,409 Tarka users. Check the latest studies of Tarka.

On Jul, 20, 2026

21 people who take Zantac and Tarka together, and have interactions are studied.

What are the common drug interactions of Zantac and Tarka, by gender? *:

female:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Fall
Pulmonary embolism (blockage of the main artery of the lung)
Hand fracture
Neuropathy peripheral (surface nerve damage)
Wrist fracture
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Chronic kidney disease
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Diarrhoea

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Fall
Fatigue (feeling of tiredness)
Fibromyalgia (a long-term condition which causes pain all over the body)
Fibula fracture
Foot fracture
Intervertebral disc degeneration (spinal disc degeneration)
Intervertebral disc protrusion (spinal disc protrusion)
Joint injury

What are the common drug interactions of Zantac and Tarka, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Steatorrhoea (presence of excess fat in faeces)
Urate nephropathy (disease or abnormality of the kidney)

60+:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pulmonary embolism (blockage of the main artery of the lung)
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
Colitis (inflammation of colon)
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Constipation
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Diarrhoea haemorrhagic (bloody diarrhoea)
Drug tolerance decreased
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

What are the existing conditions these people have? *

Pain: 7 people, 33.33%
Multiple Myeloma (cancer of the plasma cells): 5 people, 23.81%
Indigestion: 5 people, 23.81%
High Blood Cholesterol: 5 people, 23.81%
Gout (uric acid crystals building up in the body): 4 people, 19.05%
Diabetes: 4 people, 19.05%
Blood Pressure Abnormal: 4 people, 19.05%
Osteoporosis (bones weak and more likely to break): 3 people, 14.29%
Depression: 3 people, 14.29%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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