Zebeta and Lexapro drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Zebeta (bisoprolol fumarate) and Lexapro (escitalopram oxalate). Common drug interactions include anaemia among females and pain among males.
The phase IV clinical study analyzes what interactions people have when they take Zebeta and Lexapro. It is created by eHealthMe based on reports of 82 people who take the same drugs from the FDA, and is updated regularly.
What is Zebeta?
Zebeta has active ingredients of bisoprolol fumarate. It is often used in high blood pressure. eHealthMe is studying from 1,734 Zebeta users. Check the latest studies of Zebeta.
What is Lexapro?
Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,464 Lexapro users. Check the latest studies of Lexapro.
82 people who take Zebeta and Lexapro together, and have interactions are studied.

What are the common drug interactions of Zebeta and Lexapro, by gender? *:
female:
- Anaemia (lack of blood)
- Areflexia (absence of a reflex)
- Bone disorder
- Dyspnoea (difficult or laboured respiration)
- Eating disorder
- Emotional distress
- Exostosis (formation of new bone on the surface of a bone)
- Gingival pain (gum pain)
- Haemorrhoids (a swollen vein or group of veins in the region of the anus)
- Hypoaesthesia (reduced sense of touch or sensation)
male:
- Pain
- Abdominal distension
- Confusional state
- Diplopia (double vision)
- Gastrointestinal necrosis (destruction of gastrointestinal organ)
- Haemoglobin decreased
- Haemorrhage (bleeding)
- Hallucination (an experience involving the perception of something not present)
- Headache (pain in head)
- Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
What are the common drug interactions of Zebeta and Lexapro, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Gallbladder disorder
- Hepatic haemorrhage (bleeding inside liver)
- Hepatic mass
- Hepatic rupture (rapture of common benign tumour of liver)
- Injury
- Keloid scar (overgrown scars left from skin injuries)
- Pain
- Suicide attempt
30-39:
n/a
40-49:
- Headache (pain in head)
- Hyperhidrosis (abnormally increased sweating)
- Conjunctival oedema (conjunctival swelling)
- Diarrhoea
- Fatigue (feeling of tiredness)
- Hallucination, auditory (perceiving sounds without auditory stimulus)
- Intervertebral disc degeneration (spinal disc degeneration)
- Intervertebral disc protrusion (spinal disc protrusion)
- Nausea (feeling of having an urge to vomit)
- Pain
50-59:
- Emotional distress
- Exostosis (formation of new bone on the surface of a bone)
- Gingival pain (gum pain)
- Haemorrhoids (a swollen vein or group of veins in the region of the anus)
- Hypoaesthesia (reduced sense of touch or sensation)
- Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
- Impaired healing
- Ingrowing nail
- Injury
- Intervertebral disc protrusion (spinal disc protrusion)
60+:
- Haemoglobin decreased
- Haemorrhage (bleeding)
- Blood glucose increased
- Blood urea increased
- Diplopia (double vision)
- Dyspnoea (difficult or laboured respiration)
- Fall
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Gastrointestinal necrosis (destruction of gastrointestinal organ)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
What are the existing conditions these people have? *
- Hypercalcaemia (elevated calcium (ca+) level in the blood): 23 people, 28.05%
- Breast Cancer: 23 people, 28.05%
- Breast Cancer Metastatic: 22 people, 26.83%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 13 people, 15.85%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 11 people, 13.41%
- Dyspnea (difficult or laboured breathing): 7 people, 8.54%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 7 people, 8.54%
- Psoriasis (immune-mediated disease that affects the skin): 5 people, 6.10%
- Diabetes: 5 people, 6.10%
* Approximation only. Some reports may have incomplete information.
Do you take Zebeta and Lexapro?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Zebeta and Lexapro:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Zebeta:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lexapro:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zebeta and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lexapro and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on bisoprolol fumarate and escitalopram oxalate (the active ingredients of Zebeta and Lexapro, respectively), and Zebeta and Lexapro (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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